Evidence map›Paper›PMID 36689023›Full record

ArticleLasers in medical science2023

Investigation of effects of quercetin and low-level laser therapy in cisplatin-induced in vitro peripheral neuropathy model.

Simge Unay, Mehmet Dincer Bilgin

Abstract read
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Article in Lasers in medical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Simge UnayDepartment of Biophysics, Healthy Science Institute, Aydin Adnan Menderes University, TR-09100, Aydin, Turkey.ORCID https://orcid.org/0000-0002-5582-5574
Mehmet Dincer BilginDepartment of Biophysics, School of Medicine, Aydin Adnan Menderes University, 09010, Aydin, Turkey. mdbilgin@adu.edu.tr.ORCID http://orcid.org/0000-0003-0754-0854
Adnan Menderes University · TRLokman Hekim Üniversitesi · TR

Funding

Adnan Menderes Üniversitesi TPF-21002Türkiye Bilimsel ve Teknolojik Araştirma Kurumu 220S547
6 · The paper itself

Abstract

Chemotherapy-induced peripheral neuropathy (CIPN) is one of the dose-dependent side effects of cisplatin. The loss of sensory neurons is observed in CIPN. There are many methods to minimalize CIPN symptoms such as pharmacological agents and photobiostimulation but the mechanisms of these methods are unclear. Our study is aimed at determining the effects of quercetin and low-level laser therapy (LLLT) in undifferentiated and nerve growth factor-differentiated PC12 cells in cisplatin-induced peripheral neuropathy. PC12 cells with cisplatin were co-treated with quercetin and LLLT (diode pumped all-solid-state laser, 670 nm, output 500 mW, and the laser beam surface area was 1.96 cm

Indexed as

Antineoplastic AgentsLow-Level Light TherapyPeripheral Nervous System DiseasesAnimalsCisplatinGAP-43 ProteinLactate DehydrogenasesQuercetinRatsSynapsinsAntineoplastic AgentsCisplatinGAP-43 ProteinLactate DehydrogenasesQuercetinSynapsinsChemotherapy-induced peripheral neuropathyCisplatinLow-level laser therapyQuercetin

Identifiers

PMID36689023
OpenAlexW4317739143

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.