Evidence map›Paper›PMID 36688994›Full record

ArticleCancer immunology, immunotherapy : CII2023

Radiotherapy enhances CXCR3

Chih-Liang Wang, Ai-Sheng Ho, Chun-Chao Chang, Zong-Lin Sie, Cheng-Liang Peng, Jungshan Chang, Chun-Chia Cheng

Open access · hybridAbstract read
In one paragraph

Article in Cancer immunology, immunotherapy : CII, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

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  16. Evaluating the Chemical Composition and Antitumor Activity ofInternational journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Chih-Liang WangDivision of Pulmonary Oncology and Interventional Bronchoscopy, Department of Thoracic Medicine, Chang Gung Memorial Hospital, Linkou, Taoyuan, 333, Taiwan.
Ai-Sheng HoDivision of Gastroenterology, Cheng Hsin General Hospital, Taipei, 112, Taiwan.
Chun-Chao ChangDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Taipei Medical University Hospital, Taipei, 110, Taiwan.
Zong-Lin SieRadiation Biology Research Center, Institute for Radiological Research, Chang Gung University, Taoyuan, 333, Taiwan.
Cheng-Liang PengInstitute of Nuclear Energy Research, Atomic Energy Council, Taoyuan, 325, Taiwan.
Jungshan ChangGraduate Institute of Medical Sciences, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan.
Chun-Chia ChengDivision of Pulmonary Oncology and Interventional Bronchoscopy, Department of Thoracic Medicine, Chang Gung Memorial Hospital, Linkou, Taoyuan, 333, Taiwan. cccheng.biocompare@gmail.com.
Chang Gung Memorial Hospital · TWTaipei Medical University · TWChang Gung University · TWCheng Hsin General Hospital · TWInstitute of Nuclear Energy Research · TW

Funding

Cheng Gung University UMRPD1M0221Cheng Hsin General Hospital Foundation CHGH111-(N)06the Ministry of Science and Technology, Taiwan MOST 110-2314-B-182-031
6 · The paper itself

Abstract

Radiotherapy (RT) not only damages tumors but also induces interferon (IFN) expression in tumors. IFNs mediate PD-L1 to exhaust CD8

Indexed as

CD8-Positive T-LymphocytesLung NeoplasmsB7-H1 AntigenChemokine CXCL10HumansIntercellular Adhesion Molecule-1Interferon-gammaLymphocyte Function-Associated Antigen-1Receptors, CXCR3B7-H1 AntigenChemokine CXCL10CXCL10 protein, humanCXCR3 protein, humanIntercellular Adhesion Molecule-1Interferon-gammaLymphocyte Function-Associated Antigen-1Receptors, CXCR3CD8+ T cellsCXCL10CXCR3ICAM-1IFNγLung cancerPD-L1RadiotherapySTAT3

Identifiers

PMID36688994
PMCPMC10198930
OpenAlexW4317734550

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.