Evidence map›Paper›PMID 36688957›Full record

ArticleThe Journal of experimental medicine2023

Gut microbiota biofilms: From regulatory mechanisms to therapeutic targets.

Andre G Buret, Thibault Allain

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of experimental medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Vancomycin tolerance and dispersion of dual species biofilms ofbioRxiv : the preprint server for biology · 2026
    Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Insights into the Interaction BetweenJournal of personalized medicine · 2025
    Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. A thermo-resistant and RNase-sensitive cargo fromJournal of extracellular biology · 2023
    Article
  19. The Influence of Polyphenols on Atherosclerosis Development.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Andre G BuretDepartment of Biological Sciences, Host-Parasite Interactions program, Inflammation Research Network, University of Calgary , Calgary, Canada.ORCID 0000-0002-1205-5936
Thibault AllainDepartment of Biological Sciences, Host-Parasite Interactions program, Inflammation Research Network, University of Calgary , Calgary, Canada.ORCID 0000-0002-4282-1865
University of Calgary · CA

Funding

Canadian Association of Gastroenterology 1001124CIHR 20130401Crohn's and Colitis Canada 2014-05Natural Sciences and Engineering Research Council of Canada 69-0446University of Calgary 1002347
6 · The paper itself

Abstract

Gut microbiota contain communities of viruses, bacteria, fungi, and Eukarya, and live as biofilms. In health, these biofilms adhere to the intestinal mucus surface without contacting the epithelium. Disruptions to the equilibrium between these biofilms and the host may create invasive pathobionts from these commensal communities and contribute to disease pathogenesis. Environmental factors appear to dominate over genetics in determining the shifts in microbiota populations and function, including when comparing microbiota between low-income and industrialized countries. The observations discussed herein carry enormous potential for the development of novel therapies targeting phenotype in microbiota dysbiosis.

Indexed as

Gastrointestinal MicrobiomeMicrobiotaBacteriaBiofilmsDysbiosisHumansSymbiosis

Identifiers

PMID36688957
PMCPMC9884580
OpenAlexW4317777230

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.