Evidence map›Paper›PMID 36688935›Full record

ArticleDrug and alcohol dependence reports2022

Individual and social network correlates of responding to multiple overdoses among a cohort of people who use drugs.

Karla D Wagner, Charles Marks, Marisa Felsher, Carl Latkin, Jennifer L Pearson, Oluwaseun O Falade-Nwulia

Open access · goldAbstract read
In one paragraph

Article in Drug and alcohol dependence reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Trial
  2. Socioenvironmental disasters and the dialectics of overdose mortality.The International journal on drug policy · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Karla D WagnerSchool of Public Health, University of Nevada, Reno; Reno, Nevada, USA.
Charles MarksSchool of Public Health, University of Nevada, Reno; Reno, Nevada, USA.
Marisa FelsherDepartment of Medicine, Division of Infectious Diseases, Johns Hopkins School of Medicine; Baltimore, MD, USA.
Carl LatkinDepartment of Health, Behavior and Society, Johns Hopkins School of Medicine; Baltimore, MD, USA.
Jennifer L PearsonSchool of Public Health, University of Nevada, Reno; Reno, Nevada, USA.
Oluwaseun O Falade-NwuliaDepartment of Medicine, Division of Infectious Diseases, Johns Hopkins School of Medicine; Baltimore, MD, USA.
Johns Hopkins University · USUniversity of Nevada, Reno · US

Funding

Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Richard E. Chaisson · 2012 to 2026
$67.0M
The Effects of Drug Use, Depression, and Social Factors on HIV/HCV Care Continuum among PWID in Urban Areas: A Social-Network PerspectiveR01DA040488 · NIDA · JOHNS HOPKINS UNIVERSITY · PI LATKIN, CARL A, TOBIN, KARIN E · 2015 to 2020
$4.0M
The impact of social networks on hepatitis C transmission and care access in people who inject drugsK23DA041294 · NIDA · JOHNS HOPKINS UNIVERSITY · PI FALADE-NWULIA, OLUWASEUN · 2016 to 2020
$924k
NIAID NIH HHS P30 AI094189NIDA NIH HHS K23 DA041294NIDA NIH HHS R01 DA040488
6 · The paper itself

Abstract

Background: The purpose of this study was to identify characteristics of people who respond to two or more overdoses (i.e., multiple overdose responders; MOR) compared to those who respond to zero or one, and the association between MOR status and changes in network size. Methods: Secondary analysis of data from a randomized trial among 199 PWUD in Baltimore, MD (2016-2019). We used cross-tabulation, Results: From the cohort of 199, 185 people provided data on overdose response at baseline; 197 provided data at 6-month follow-up. At baseline, 27.6% of participants were classified as MORs (ever). Correlates of MOR status included homelessness; age; injecting drug use; quality of interactions with police (respectful vs. not); and use of powder cocaine, prescription opioids, and heroin. MORs had larger networks and their network size decreased more over time, but the association was not statistically significant. At follow-up, 16% were classified as MORs (past 6 months); correlates of follow-up MOR status were similar to those at baseline. Conclusions: Overdose prevention interventions rely on PWUD to respond to overdoses. Identifying factors associated with MOR status could increase intervention efficiency and providing MORs with support could increase sustainability. Our findings suggest that PWUD experiencing homelessness, using cocaine and heroin, and demonstrating increased salience of overdose in their lives would benefit from targeted programs.

Indexed as

BaltimoreNaloxoneOverdose preventionPeople who use drugsSocial networks

Identifiers

PMID36688935
PMCPMC9854250
OpenAlexW4302773915

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.