Evidence map›Paper›PMID 36688522›Full record

ReviewBiomaterials science2023

Harnessing the potential of oxygen-generating materials and their utilization in organ-specific delivery of oxygen.

Vasilios K Nikolopoulos, Robin Augustine, Gulden Camci-Unal

Open access · greenAbstract readReview
In one paragraph

Review in Biomaterials science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Vasilios K NikolopoulosDepartment of Chemical Engineering, University of Massachusetts, Lowell, Massachusetts 01854, USA. Gulden_CamciUnal@uml.edu.ORCID http://orcid.org/0000-0002-0384-0713
Robin AugustineDepartment of Chemical Engineering, University of Massachusetts, Lowell, Massachusetts 01854, USA. Gulden_CamciUnal@uml.edu.ORCID http://orcid.org/0000-0001-9724-8392
Gulden Camci-UnalDepartment of Chemical Engineering, University of Massachusetts, Lowell, Massachusetts 01854, USA. Gulden_CamciUnal@uml.edu.ORCID http://orcid.org/0000-0003-4258-844X
University of Massachusetts Lowell · US

Funding

Scaffolds with high oxygen content for mineralizationR01DE030129 · NIDCR · UNIVERSITY OF MASSACHUSETTS LOWELL · PI CAMCI-UNAL, GULDEN · 2021 to 2025
$2.0M
NIDCR NIH HHS R01 DE030129
6 · The paper itself

Abstract

The limited availability of transplantable organs hinders the success of patient treatment through organ transplantation. In addition, there are challenges with immune rejection and the risk of disease transmission when receiving organs from other individuals. Tissue engineering aims to overcome these challenges by generating functional three-dimensional (3D) tissue constructs. When developing tissues or organs of a particular shape, structure, and size as determined by the specific needs of the therapeutic intervention, a tissue specific oxygen supply to all parts of the tissue construct is an utmost requirement. Moreover, the lack of a functional vasculature in engineered tissues decreases cell survival upon implantation in the body. Oxygen-generating materials can alleviate this challenge in engineered tissue constructs by providing oxygen in a sustained and controlled manner. Oxygen-generating materials can be incorporated into 3D scaffolds allowing the cells to receive and utilize oxygen efficiently. In this review, we present an overview of the use of oxygen-generating materials in various tissue engineering applications in an organ specific manner as well as their potential use in the clinic.

Indexed as

OxygenTissue ScaffoldsCell SurvivalHumansTissue EngineeringOxygen

Identifiers

PMID36688522
PMCPMC10015602
OpenAlexW4317778266

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.