Evidence map›Paper›PMID 36688453›Full record

ArticleInflammatory bowel diseases2023

Inflammatory Bowel Disease Among Canadian Children: Comparison Between Children of Non-European Descent and Children of European Descent.

Jocelyn Jeong, Thomas D Walters, Hien Q Huynh, Sally Lawrence, David R Mack, Colette Deslandres, Anthony Otley, Wael El-Matary, Mary Sherlock, Anne M Griffiths and 14 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Inflammatory bowel diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 11 institutions in 1 country.

Jocelyn JeongDepartment of Community Health Services, University of Calgary, Calgary, AB, Canada.ORCID 0000-0002-8989-2361
Thomas D WaltersSickKids Inflammatory Bowel Disease Centre, Division of Pediatric Gastroenterology, Hepatology and Nutrition, Hospital for Sick Children, Department of Paediatrics, University of Toronto, Toronto, ON, Canada.
Hien Q HuynhEdmonton Pediatric IBD Clinic, Department of Pediatrics, University of Alberta, Edmonton, AB, Canada.
Sally LawrenceDivision of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, BC Children's Hospital, University of British Columbia, Vancouver, BC, Canada.
David R MackDivision of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, Canada.
Colette DeslandresDepartment of Pediatrics, CHU Sainte-Justine, Montréal, QC, Canada.
Anthony OtleyDivision of Pediatric Gastroenterology & Nutrition, Department of Pediatrics, IWK Health Centre, Dalhousie University, Halifax, NS, Canada.
Wael El-MatarySection of Pediatric Gastroenterology, Winnipeg Children's Hospital, University of Manitoba, Winnipeg, MB, Canada.ORCID 0000-0001-6417-7583
Mary SherlockDivision of Pediatric Gastroenterology, McMaster Children's Hospital, Hamilton, ON, Canada.
Anne M GriffithsSickKids Inflammatory Bowel Disease Centre, Division of Pediatric Gastroenterology, Hepatology and Nutrition, Hospital for Sick Children, Department of Paediatrics, University of Toronto, Toronto, ON, Canada.
Eytan WineEdmonton Pediatric IBD Clinic, Department of Pediatrics, University of Alberta, Edmonton, AB, Canada.
Kevan JacobsonDivision of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, BC Children's Hospital, University of British Columbia, Vancouver, BC, Canada.ORCID 0000-0001-7269-8557
Peter ChurchSickKids Inflammatory Bowel Disease Centre, Division of Pediatric Gastroenterology, Hepatology and Nutrition, Hospital for Sick Children, Department of Paediatrics, University of Toronto, Toronto, ON, Canada.
Matthew W CarrollEdmonton Pediatric IBD Clinic, Department of Pediatrics, University of Alberta, Edmonton, AB, Canada.
Eric I BenchimolSickKids Inflammatory Bowel Disease Centre, Division of Pediatric Gastroenterology, Hepatology and Nutrition, Hospital for Sick Children, Department of Paediatrics, University of Toronto, Toronto, ON, Canada.
Herbert BrillDivision of Pediatric Gastroenterology, McMaster Children's Hospital, Hamilton, ON, Canada.
Jeff CritchDepartment of Pediatrics, Janeway Children's Hospital, St. John's, NL, Canada.
Kevin BaxDepartment of Pediatrics, Schulich School of Medicine, Western University, Children's Hospital of Western Ontario, London, ON, Canada.
Prévost JantchouDepartment of Pediatrics, CHU Sainte-Justine, Montréal, QC, Canada.
Mohsin RashidDivision of Pediatric Gastroenterology & Nutrition, Department of Pediatrics, IWK Health Centre, Dalhousie University, Halifax, NS, Canada.
Gilaad G KaplanDepartment of Community Health Services, University of Calgary, Calgary, AB, Canada.
Cynthia H SeowDepartment of Community Health Services, University of Calgary, Calgary, AB, Canada.
Kerri NovakDepartment of Medicine, University of Calgary, Calgary, AB, Canada.ORCID 0000-0003-4164-7321
Jennifer C deBruynDepartment of Community Health Services, University of Calgary, Calgary, AB, Canada.
University of Calgary · CAUniversity of Toronto · CAUniversity of Alberta · CAUniversity of British Columbia · CACentre Hospitalier Universitaire Sainte-Justine · CADalhousie University · CAMcMaster Children's Hospital · CAChildren's Hospital of Winnipeg · CAJaneway Children's Health and Rehabilitation Centre · CAUniversity of Ottawa · CAWestern University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInflammatory bowel disease (IBD) phenotypes may differ between countries and ancestral groups. The study aim was to examine ancestry and subtype variations of children newly diagnosed with IBD.

methodsChildren newly diagnosed with IBD enrolled into the Canadian Children Inflammatory Bowel Disease Network inception cohort study were categorized into 8 ancestral groups. Prospectively collected data at diagnosis and follow-up were compared between ancestral groups.

resultsAmong 1447 children (63.2% Crohn's disease, 30.7% ulcerative colitis), 67.8% were European, 9.4% were South Asian, 3.8% were West Central Asian and Middle Eastern, 2.3% were African, 2.2% were East/South East Asian, 2.0% were Caribbean/Latin/Central/South American, 9.9% were mixed, and 2.6% were other. Children of African descent with ulcerative colitis had an older age of diagnosis compared with children of European descent (median 15.6 years vs 13.3 years; P = .02). Children of European descent had a higher proportion of positive family history with IBD (19.3% vs 12.1%; P = .001) compared with children of non-European descent. Children of European descent also had a lower proportion of immigrants and children of immigrants compared with children of non-European descent (9.8% vs 35.9%; P < .0001; and 3.6% vs 27.2%; P < .0001, respectively) .

conclusionsImportant differences exist between different ancestral groups in pediatric patients with IBD with regard to age of diagnosis, family history, and immigrant status. Our study adds to the knowledge of the impact of ancestry on IBD pathogenesis.

Indexed as

Colitis, UlcerativeCrohn DiseaseInflammatory Bowel DiseasesCanadaChildCohort StudiesHumansancestrychildrencohort studyinflammatory bowel disease

Identifiers

PMID36688453
PMCPMC10628923
OpenAlexW4317745704

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.