ArticleJournal of the American Heart Association2023
Association of Depression and Poor Mental Health With Cardiovascular Disease and Suboptimal Cardiovascular Health Among Young Adults in the United States.
Article in Journal of the American Heart Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers, 2 of them syntheses that pooled it.
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Who cites it
72 citing papers in PubMed, 2 syntheses or guidelines pooled it, 109 citations in OpenAlex.
- The relationship between cardiovascular health and common mental disorders among adults aged ≤ 50 years: a systematic review of observational studies.BMC psychiatry · 2026Pooled it
- Depression and cardiovascular disease: mind the gap in the guidelines.European heart journal · 2025Pooled it
- The impact of educational intervention on enhancing the health literacy among middle-aged individuals at risk for cardiovascular diseases: a randomized cotrolled trial.BMC public health · 2025Trial
- Microglia promote vascular remodeling in a mouse model of chronic stress.Brain, behavior, and immunity · 2026Article
- FlowVM-Net: Enhanced Vessel Segmentation in X-Ray Coronary Angiography Using Temporal Information Fusion.Journal of imaging informatics in medicine · 2026Article
- Machine Learning Approaches to Identify Influential Factors of the Comorbid Psychiatric Symptoms and Hypertension Among Rural Adults in Bangladesh: A Cross-Sectional Study.Health science reports · 2026Article
- Longitudinal Associations of Cumulative Depression Burden With Cardiovascular Diseases and All-Cause Death Among Middle-Aged and Older Population: Evidence From 2 Nationwide Cohort Studies.Journal of the American Heart Association · 2026Article
- Process Evaluation of a Parish-Based Intervention to Reduce Mental Health-Related Stigma.Community mental health journal · 2026Article
- Yorga Moorditj Koort: Aboriginal and Torres Strait Islander women's perspectives about heart health on Noongar Boodjar.Health promotion international · 2026Article
- The interplay between loneliness, cortisol, and NK cell function: The role of cortisol in NK cell dysfunction.Psychoneuroendocrinology · 2026Article
- PGS Browser: a public platform for personalized polygenic score analysis and interpretation.Nature communications · 2026Article
- Cardiac rhythm development: A wearable device index of risk for physical and mental illness in adolescence.medRxiv : the preprint server for health sciences · 2026Article
- Beyond Traditional Risk Factors: The Role of Mental Health and Intersectionality in Cardiovascular Disease Risk Prediction Models.Journal of the American Heart Association · 2026Article
- Trajectories of depressive symptoms across pregnancy and the extended postpartum period and future cardiovascular health.medRxiv : the preprint server for health sciences · 2026Article
- Psychological Health, Polysocial Risk, and Cardiovascular Health Among Women of Reproductive Age.JACC. Advances · 2026Article
- Coronary Artery Disease and Loneliness: A Cross-Sectional Analysis using the Revised UCLA Loneliness Scale.The International journal of angiology : official publication of the International College of Angiology, Inc · 2026Article
- Association between depressive symptoms and atherosclerotic cardiovascular disease: a Swedish population-based cohort study.BMC cardiovascular disorders · 2026Article
- Relationship of Depression With Incident Cardiovascular Disease in Individuals With Chronic Kidney Disease.Circulation reports · 2026Article
- Association between PMBMC public health · 2026Article
- Depression and the risk of myocardial infarction: evidence from a cross-sectional analysis of NHANES 2005-2020.Annals of general psychiatry · 2026Article
12 more citing papers are in PubMed but not listed here.
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Authors and funding
12 authors at 4 institutions in 2 countries.
Funding
Abstract
Background Depression is a nontraditional risk factor for cardiovascular disease (CVD). Data on the association of depression and poor mental health with CVD and suboptimal cardiovascular health (CVH) among young adults are limited. Methods and Results We used data from 593 616 young adults (aged 18-49 years) from the 2017 to 2020 Behavioral Risk Factor Surveillance System, a nationally representative survey of noninstitutionalized US adults. Exposures were self-reported depression and poor mental health days (PMHDs; categorized as 0, 1-13, and 14-30 days of poor mental health in the past 30 days). Outcomes were self-reported CVD (composite of myocardial infarction, angina, or stroke) and suboptimal CVH (≥2 cardiovascular risk factors: hypertension, hypercholesterolemia, overweight/obesity, smoking, diabetes, physical inactivity, and inadequate fruit and vegetable intake). Using logistic regression, we investigated the association of depression and PMHDs with CVD and suboptimal CVH, adjusting for sociodemographic factors (and cardiovascular risk factors for the CVD outcome). Of the 593 616 participants (mean age, 34.7±9.0 years), the weighted prevalence of depression was 19.6% (95% CI, 19.4-19.8), and the weighted prevalence of CVD was 2.5% (95% CI, 2.4-2.6). People with depression had higher odds of CVD than those without depression (odds ratio [OR], 2.32 [95% CI, 2.13-2.51]). There was a graded association of PMHDs with CVD. Compared with individuals with 0 PMHDs, the odds of CVD in those with 1 to 13 PMHDs and 14 to 30 PHMDs were 1.48 (95% CI, 1.34-1.62) and 2.29 (95% CI, 2.08-2.51), respectively, after adjusting for sociodemographic and cardiovascular risk factors. The associations did not differ significantly by sex or urban/rural status. Individuals with depression had higher odds of suboptimal CVH (OR, 1.79 [95% CI, 1.65-1.95]) compared with those without depression, with a similar graded relationship between PMHDs and suboptimal CVH. Conclusions Depression and poor mental health are associated with premature CVD and suboptimal CVH among young adults. Although this association is likely bidirectional, prioritizing mental health may help reduce CVD risk and improve CVH in young adults.
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