Evidence map›Paper›PMID 36688232›Full record

ArticleSSM. Mental health2022

Intimate partner violence and HIV treatment adherence in urban South Africa: Mediating role of perinatal common mental disorders.

A M Hatcher, J M Turan, H Stöckl, N Woollett, C Garcia-Moreno, N J Christofides

Open access · goldAbstract read
In one paragraph

Article in SSM. Mental health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 6 countries.

A M HatcherGillings School of Global Public Health, University of North Carolina, Chapel Hill, United States.
J M TuranSchool of Public Health, University of Alabama at Birmingham, Birmingham, AL, United States.
H StöcklThe Institute for Medical Information Processing, Biometry, and Epidemiology, Ludwig-Maximilians-University, Munich, Germany.
N WoollettSchool of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
C Garcia-MorenoDepartment of Reproductive Health and Research, World Health Organization, Geneva, Switzerland.
N J ChristofidesSchool of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
University of the Witwatersrand · ZAKoç University · TRLondon School of Hygiene & Tropical Medicine · GBUniversity of North Carolina at Chapel Hill · USWorld Health Organization · CH

Funding

Mechanisms and pilot intervention for addressing intimate partner violence and HIV in antenatal careK01MH121185 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HATCHER, ABIGAIL MAE · 2019 to 2023
$820k
NIMH NIH HHS K01 MH121185World Health Organization 001
6 · The paper itself

Abstract

Background: Antiretroviral therapy (ART) has potential to eliminate perinatal HIV infections, but adherence to ART in late pregnancy and postpartum is often suboptimal. Intimate partner violence (IPV) may influence non-adherence among perinatal women living with HIV (WWH), but few quantitative studies have examined this over time or explored mechanisms for this association. Methods: We used secondary data from a parent trial in Johannesburg comprising WWH from the control arm ( Results: Of 196 perinatal WWH, 53.1% reported IPV exposure at baseline. The majority of participants (85.7%) had good perinatal ART adherence. In adjusted models, IPV at baseline was associated with halved odds of good adherence (aOR=0.51, 95%CI=0.20-0.96). IPV was associated with higher adjusted odds of probable depression (aOR=4.64), anxiety (aOR=2.85), and PTSD (aOR=3.42). In SEM, IPV had a direct (standardized coef=-0.22) and indirect effect (coef=-0.05) on ART via common mental disorders. The total effect of IPV on perinatal adherence was of moderate size (coef= -0.27) and the model had good fit (CFI=0.972; TLI=0.969; RMSEA=0.045; SRMR=0.076). Conclusion: IPV was longitudinally associated with perinatal ART non-adherence in part due to its relationship with mental health symptomology. Addressing IPV within clinical care has potential to improve perinatal mental health, maternal HIV outcomes, and HIV-free infant survival.

Indexed as

Antiretroviral adherenceART, antiretroviral therapyHIVHIV, human immonodeficiency virusIntimate partner violenceIPV, intimate partner violencePerinatal common mental disordersPTSD, post-traumatic stress disorderStructural equation modelingT0, baseline timepointT1, endline timepointWWH, women living with HIV

Identifiers

PMID36688232
PMCPMC9792377
OpenAlexW4280604594

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.