ArticleFrontiers in aging neuroscience2022
Alterations of color vision and pupillary light responses in age-related macular degeneration.
Article in Frontiers in aging neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 15 citations in OpenAlex.
- Discordance Between Eye-Specific Clinical Outcomes and Patient-Reported Visual Function After Faricimab Treatment for Neovascular Age-Related Macular Degeneration: A Two-Case Report.Vision (Basel, Switzerland) · 2026Article
- Recovery of the Pupillary Response After Light Adaptation Is Slowed in Patients with Age-Related Macular Degeneration.Journal of eye movement research · 2025Article
- Association Between Eye Diseases and Sleep Duration: A Nationwide Cross-Sectional Study.Psychiatry investigation · 2025Article
- Clinical Applications of the Cone Contrast Test in Ophthalmology and Neurology.Journal of clinical medicine · 2025Review
- Frequency tagged multifocal pupillary response fields identify age-related macular degeneration and diabetic retinopathy.Frontiers in neuroscience · 2025Article
- Color memory as a diagnostic test for mild cognitive impairment and early stage of Alzheimer's disease.Frontiers in neurology · 2025Article
- Dynamic Pupillary Responses in Age-Related Macular Degeneration: A Controlled Clinical Study Using High-Frequency Video-Oculography.Clinical ophthalmology (Auckland, N.Z.) · 2025Article
- Basics, benefits, and pitfalls of pupillometers assessing visual function.Eye (London, England) · 2024Review
- The prevalence of red-green color vision deficiency and its related factors in an elderly population above 60 years of age.International journal of ophthalmology · 2023Article
- Sleep duration and age-related macular degeneration: a cross-sectional and Mendelian randomization study.Frontiers in aging neuroscience · 2023Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Age-related macular degeneration (AMD) is the leading cause of irreversible central vision loss in developed countries and one of the leading causes of blindness. In this work, we evaluated color vision and the pupil light reflex (PLR) to assess visual function in patients with early and neovascular AMD (NVAMD) compared with the control group. Methods: We recruited 34 early patients with dry AMD and classified them into two groups following AREDS: 13 patients with NVAMD and 24 healthy controls. Controls and patients with early dry AMD had visual acuity (VA) best or equal to 20/25 (0.098 logMAR). Color vision was assessed in controls and patients with early dry AMD using the Cambridge Color Test (CCT) 2.0 through the Trivector protocol. The PLR was evaluated using a Ganzfeld, controlled by the RETI-port system. The stimuli consisted of 1s blue (470 nm) and red (631 nm) light flashes presented alternately at 2-min intervals. To assess the cone contribution, we used a red flash at 2.4 log cd.m Results: Patients with early dry AMD had reduced color discrimination in all three axes: protan ( Conclusion: Patients with early dry AMD present diffusely acquired color vision alteration detected by CCT. Rods and melanopsin contributions for PLR are affected in NVAMD. The CCT and the PLR may be considered sensitive tests to evaluate and monitor functional changes in patients with AMD.
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