Evidence map›Paper›PMID 36688134›Full record

ArticleFrontiers in behavioral neuroscience2022

Anterior cingulate cortex, but not amygdala, modulates the anxiogenesis induced by living with conspecifics subjected to chronic restraint stress in male mice.

Lara Maria Silveira, Ligia Renata Rodrigues Tavares, Daniela Baptista-de-Souza, Isabela Miranda Carmona, Paulo Eduardo Carneiro de Oliveira, Ricardo Luiz Nunes-de-Souza, Azair Canto-de-Souza

Abstract read
In one paragraph

Article in Frontiers in behavioral neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Contagion of depression: a double-edged sword.Translational psychiatry · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lara Maria SilveiraPsychobiology Group, Department of Psychology/Centro de Educação e Ciências Humanas (CECH), Universidade Federal de São Carlos, São Carlos, São Paulo, Brazil.
Ligia Renata Rodrigues TavaresPsychobiology Group, Department of Psychology/Centro de Educação e Ciências Humanas (CECH), Universidade Federal de São Carlos, São Carlos, São Paulo, Brazil.
Daniela Baptista-de-SouzaPsychobiology Group, Department of Psychology/Centro de Educação e Ciências Humanas (CECH), Universidade Federal de São Carlos, São Carlos, São Paulo, Brazil.
Isabela Miranda CarmonaPsychobiology Group, Department of Psychology/Centro de Educação e Ciências Humanas (CECH), Universidade Federal de São Carlos, São Carlos, São Paulo, Brazil.
Paulo Eduardo Carneiro de OliveiraPsychobiology Group, Department of Psychology/Centro de Educação e Ciências Humanas (CECH), Universidade Federal de São Carlos, São Carlos, São Paulo, Brazil.
Ricardo Luiz Nunes-de-SouzaJoint Graduate Program in Physiological Sciences, Universidade Federal de São Carlos (UFSCar)/Universidade Estadual Paulista (UNESP), São Carlos, São Paulo, Brazil.
Azair Canto-de-SouzaPsychobiology Group, Department of Psychology/Centro de Educação e Ciências Humanas (CECH), Universidade Federal de São Carlos, São Carlos, São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cohabitation with a partner undergoing chronic restraint stress (CRE) induces anxiogenic-like behaviors through emotional contagion. We hypothesized that the anterior cingulate cortex (ACC) and the amygdala would be involved in the modulation of this emotional process. This study investigated the role of the ACC and amygdala in empathy-like behavior (e.g., anxiety-like responses) induced by living with a mouse subjected to CRE. Male Swiss mice were housed in pairs for 14 days and then allocated into two groups: cagemate stress (one animal of the pair was subjected to 14 days of restraint stress) and cagemate control (no animal experienced stress). Twenty-four hours after the last stress session, cagemates had their brains removed for recording FosB labeling in the ACC and amygdala (Exp.1). In experiments 2 and 3, 24 h after the last stress session, the cagemates received 0.1 μL of saline or cobalt chloride (CoCl

Indexed as

amygdalaanterior cingulate cortexanxietychronic restraint stressempathymice

Identifiers

PMID36688134
PMCPMC9853544

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.