Evidence map›Paper›PMID 36687950›Full record

ArticleFrontiers in psychology2022

The quality of life in patients with multiple sclerosis - Association with depressive symptoms and physical disability: A prospective and observational study.

Aleksandra Kołtuniuk, Beata Pawlak, Dorota Krówczyńska, Justyna Chojdak-Łukasiewicz

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
10.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Article
  3. Kinesiophobia in Multiple Sclerosis: Associations with Age, Anxiety, and Physical Activity.Medical science monitor : international medical journal of experimental and clinical research · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Quality of life and access to treatment for patients with multiple sclerosis during economic crisis: the Lebanese experience.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
  8. Impact of Depression, Fatigue, and Pain on Quality of Life in Slovak Multiple Sclerosis Patients.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Article
  9. Review
  10. Article
  11. Behavioral disorders in multiple sclerosis: a comprehensive review.Journal of neural transmission (Vienna, Austria : 1996) · 2025
    Review
  12. Article
  13. Article
  14. Article
  15. Depressive Symptoms in Multiple Sclerosis: Links to Body Composition, Physical Activity, and Functional Ability.Medical science monitor : international medical journal of experimental and clinical research · 2024
    Article
  16. Review
  17. Depression and anxiety in multiple sclerosis. Review of a fatal combination.Journal of neural transmission (Vienna, Austria : 1996) · 2024
    Review
  18. Review
  19. Article
  20. Perceived health- related quality of life in persons with multiple sclerosis with and without a vascular comorbidity.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Aleksandra KołtuniukDivision of Internal Medicine Nursing, Wroclaw Medical University, Wroclaw, Poland.
Beata PawlakDivision of Internal Medicine Nursing, Wroclaw Medical University, Wroclaw, Poland.
Dorota KrówczyńskaCardinal Stefan Wyszynski Institute of Cardiology, Warsaw, Poland.
Justyna Chojdak-ŁukasiewiczDepartment of Neurology, Wroclaw Medical University, Wroclaw, Poland.
Wroclaw Medical University · PLCollegium Mazovia Innowacyjna Szkoła Wyższa · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Patients with multiple sclerosis (MS) experience disabilities which significantly affect their quality of life (QOL) and mental health. Mood disorders and depressive symptoms are one of the most common psychiatric conditions in MS patients. This study aimed to evaluate the level of QOL in MS patients and to assess the influence of depressive symptoms and physical disability on QOL. Methods: This prospective and observational study was conducted among 100 MS patients (mean age of 36.23 ± 11.77) recruited from the Lower Silesian Unit of the Polish Association for Multiple Sclerosis. This study used a questionnaire designed by the authors, which contained questions about sociodemographic and clinical data, as well as the following standardized questionnaires: the Activities of Daily Living questionnaire (ADL), the Instrumental Activities of Daily Living questionnaire (IADL), the Expanded Disability Status Scale (EDSS), the Beck Depression Inventory (BDI) and Multiple Sclerosis International Quality of Life Questionnaire (MusiQOL). Results: The average EDSS score among patients was 3.13 ± 2.38 points. More than half of the respondents (68%) suffered from depression of varying severity. The univariate linear regression models showed that the independent ( Conclusion: Depressive symptoms significantly affect the QOL of MS patients.

Indexed as

daily activitiesdepressionmental healthmultiple sclerosisnursingquality of life

Identifiers

PMID36687950
PMCPMC9853525
OpenAlexW4313625315

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.