ArticleFrontiers in nutrition2022
Prognostic nutritional index: A potential biomarker for predicting the prognosis of decompensated liver cirrhosis.
Article in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Prognostic nutritional index as a predictor of ursodeoxycholic acid response in primary biliary cholangitis: a retrospective study.BMC gastroenterology · 2026Article
- Integrated routine laboratory indices for risk stratification in HBV-related cirrhosis: a real-world study.BMC gastroenterology · 2026Article
- Development and validation of a model for predicting short-term complications after hepatectomy in patients with primary liver cancer.Journal of gastrointestinal oncology · 2026Article
- The prognostic nutritional index improves risk stratification for acute pulmonary embolism.iScience · 2026Article
- The prognostic nutritional index vs. MELD for short-term mortality in critically ill liver disease: a retrospective multi-cohort study.Frontiers in nutrition · 2026Article
- Pan immune inflammation value improves MELD 3.0 for mortality prediction in critically ill cirrhotic patients.Scientific reports · 2025Article
- Systemic inflammatory indexes as predictors of 18-month mortality among cirrhotic patients receiving transjugular intrahepatic portosystemic shunt.Annals of medicine · 2025Article
- Inflammatory and nutritional indices for overall survival in Hemodialysis patients: a multicenter cohort study.BMC nephrology · 2025Article
- The prognostic nutritional index is an effective prognostic and nutritional status indicator for cirrhosis.BMC gastroenterology · 2025Article
- Impact of nutritional status and pulmonary function on short- and long-term overall survival in hemodialysis patients.PloS one · 2025Article
- Association of Immune Nutrition Indices with the Risk of All-Cause Mortality and Cardiovascular Mortality in Patients with Heart Failure in the NHANES (1999-2018).Reviews in cardiovascular medicine · 2025Article
- Prognostic nutritional index as a potential predictor of prognosis in patients with sepsis: a retrospective cohort study.Frontiers in nutrition · 2025Article
- Joint effects of prognostic nutritional index and skeletal muscle index on prognosis of decompensated cirrhosis: a retrospective cohort study.Therapeutic advances in chronic disease · 2025Article
- Research progress on nutritional support for patients with liver cirrhosis complicated by upper gastrointestinal bleeding.Frontiers in nutrition · 2025Review
- Impact of the prognostic nutritional index on the recompensation of patients with decompensated primary biliary cholangitis.Frontiers in immunology · 2025Article
- Prognostic nutritional index and systemic inflammation index as predictors of cirrhosis severity: a cross-sectional study.Gastroenterology and hepatology from bed to bench · 2025Article
- Long-term outcomes of endoscopic resection of superficial esophageal squamous cell carcinoma in late-elderly patients.Journal of gastroenterology and hepatology · 2024Article
- Artificial intelligence-based evaluation of prognosis in cirrhosis.Journal of translational medicine · 2024Review
- Association of Systemic Inflammation Response Index with Short-Term All-Cause Mortality in Decompensated Liver Cirrhosis Patients.Journal of inflammation research · 2024Article
- Prognostic Nutritional Index Correlates with Liver Function and Prognosis in Chronic Liver Disease Patients.Diagnostics (Basel, Switzerland) · 2023Article
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Abstract
Background: Prognostic nutritional index (PNI) is an independent predictor of the prognosis of various diseases. However, the prognosis value of PNI in patients with decompensated liver cirrhosis (DLC) remains unknown. The study aimed to investigate the prognostic significance of PNI in patients with DLC. Methods: A total of 214 eligible patients were enrolled in the study's development cohort between January 2018 and March 2021. The clinical primary study endpoints were mortality at 3 and 6 months. Receiver operating characteristic (ROC) curve analysis was used to assess the PNI's prediction accuracy, and Youden's index was utilized to determine the PNI's optimal cut-off value. Moreover, based on the optimal cut-off value, patients were categorized into high and low PNI groups. Multivariate logistic regression analysis was used to determine independent risk factors for mortality, while the relationship between PNI and the risk of death was identified and demonstrated using restricted cubic splines (RCS). A validation cohort of 139 patients was to verify the predictive power of the PNI. Results: In the development cohort, the mortality rate at 3 and 6 months were 10.3% (22) and 14.0% (30), respectively. The PNI had comparable predictive power with the MELD score at all follow-up endpoints. Decreased PNI was an independent predictor of adverse prognosis at all follow-up endpoints. The RCS revealed a linear correlation between PNI and the risk of death. We confirmed that lower PNI was an independent predictor of poor prognosis in the validation cohort. Conclusion: The findings showed that lower PNI is an independent factor of poor outcomes and might be utilized as a potentially promising prognostic predictor in patients with DLC.
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