Evidence map›Paper›PMID 36687649›Full record

ArticleFrontiers in microbiology2022

Maternal diet associated with infants' intestinal microbiota mediated by predominant long-chain fatty acid in breast milk.

Menglu Xi, Xiaona Na, Xia Ma, Hanglian Lan, Ting Sun, Wei-Hsien Liu, Weilian Hung, Ai Zhao

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Menglu XiVanke School of Public Health, Tsinghua University, Beijing, China.
Xiaona NaVanke School of Public Health, Tsinghua University, Beijing, China.
Xia MaInner Mongolia Dairy Technology Research Institute Co., Ltd., Hohhot, China.
Hanglian LanInner Mongolia Dairy Technology Research Institute Co., Ltd., Hohhot, China.
Ting SunInner Mongolia Dairy Technology Research Institute Co., Ltd., Hohhot, China.
Wei-Hsien LiuInner Mongolia Dairy Technology Research Institute Co., Ltd., Hohhot, China.
Weilian HungInner Mongolia Dairy Technology Research Institute Co., Ltd., Hohhot, China.
Ai ZhaoVanke School of Public Health, Tsinghua University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Long-chain fatty acids in breast milk are affected by the mother's diet and play an important role in the growth, development, and immune construction of infants. This study aims to explore the correlation between maternal diet, breast milk fatty acids (FAs), and the infant intestinal flora. Methods: We enrolled 56 paired mothers and their infants; both breast milk samples and infants' fecal samples were collected to determine the long-chain FA content of breast milk by ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS), and metagenomic technology was applied to determine the microbial composition of infant feces. The maternal diet was also investigated using a 24-h dietary recall. Results: The results indicated that the fat contribution rates of edible oils in the maternal diet are significantly positively correlated with the contents of certain long-chain fatty acids (C16:0, C18:1, C16:1, and C22:4) in breast milk, which mainly regulate the abundance of Discussion: The results of this study suggest a pathway in which the diets of lactating mothers may affect the composition of the infant intestinal microbiota by influencing breast milk FAs and then further regulating infant health.

Indexed as

breast milkinfant microbiotaKEGGlong-chain fatty acidsmetagenomics sequencing

Identifiers

PMID36687649
PMCPMC9852834

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.