Evidence map›Paper›PMID 36687526›Full record

ArticleFrontiers in cellular neuroscience2022

Single cell RNA sequencing analysis of mouse cochlear supporting cell transcriptomes with activated ERBB2 receptor indicates a cell-specific response that promotes CD44 activation.

Dorota Piekna-Przybylska, Daxiang Na, Jingyuan Zhang, Cameron Baker, John M Ashton, Patricia M White

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Frontiers in cellular neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Pharmacological Approaches to Hearing Loss.Pharmacological reviews · 2024
    Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Dorota Piekna-PrzybylskaDepartment of Neuroscience, University of Rochester School of Medicine and Dentistry, Rochester, NY, United States.
Daxiang NaDepartment of Neuroscience, University of Rochester School of Medicine and Dentistry, Rochester, NY, United States.
Jingyuan ZhangDepartment of Biology, University of Rochester, Rochester, NY, United States.
Cameron BakerGenomic Research Center, University of Rochester School of Medicine and Dentistry, Rochester, NY, United States.
John M AshtonGenomic Research Center, University of Rochester School of Medicine and Dentistry, Rochester, NY, United States.
Patricia M WhiteDepartment of Neuroscience, University of Rochester School of Medicine and Dentistry, Rochester, NY, United States.
University of Rochester · US

Funding

Supplemental grant to Sufficiency of ErbB2 signaling in murine supporting cell proliferationR01DC014261 · NIDCD · UNIVERSITY OF ROCHESTER · PI WHITE, PATRICIA M. · 2015 to 2019
$2.2M
Foxo3 Mechanisms in Noise DamageR01DC018660 · NIDCD · UNIVERSITY OF ROCHESTER · PI WHITE, PATRICIA M. · 2021 to 2025
$1.7M
NIDCD NIH HHS R01 DC014261
6 · The paper itself

Abstract

Hearing loss caused by the death of cochlear hair cells (HCs) might be restored through regeneration from supporting cells (SCs)

Indexed as

candidate pathwayCD44cochlear regenerationERBB2SIBLINGsingle cell sequencing

Identifiers

PMID36687526
PMCPMC9853549
OpenAlexW4313624536

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.