Evidence map›Paper›PMID 36687361›Full record

ArticleERJ open research2023

Early selexipag initiation and long-term outcomes: insights from randomised controlled trials in pulmonary arterial hypertension.

J Gerry Coghlan, Sean Gaine, Richard Channick, Kelly M Chin, Camille du Roure, J Simon R Gibbs, Marius M Hoeper, Irene M Lang, Stephen C Mathai, Vallerie V McLaughlin and 5 more

Open access · goldAbstract read
In one paragraph

Article in ERJ open research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 17 citations in OpenAlex.

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  7. Treatment algorithm for pulmonary arterial hypertension.The European respiratory journal · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 13 institutions in 8 countries.

J Gerry CoghlanRoyal Free Hospital, London, UK.
Sean GaineMater Misericordiae University Hospital, Dublin, Ireland.
Richard ChannickDavid Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Kelly M ChinUT Southwestern Medical Center, Dallas, TX, USA.
Camille du RoureActelion Pharmaceuticals Ltd, a Janssen Pharmaceutical Company of Johnson & Johnson, Global Medical Affairs, Allschwil, Switzerland.
J Simon R GibbsNational Heart and Lung Institute, Imperial College London, London, UK.
Marius M HoeperDepartment of Respiratory Medicine, Hannover Medical School and German Center for Lung Research, Hannover, Germany.ORCID https://orcid.org/0000-0001-9086-2293
Irene M LangDivision of Cardiology, Medical University of Vienna, Vienna, Austria.
Stephen C MathaiJohns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID https://orcid.org/0000-0003-3188-7209
Vallerie V McLaughlinUniversity of Michigan, Ann Arbor, MI, USA.
Lada MitchellActelion Pharmaceuticals Ltd, a Janssen Pharmaceutical Company of Johnson & Johnson, Statistics & Decision Sciences - Medical Affairs and Established Products, Allschwil, Switzerland.
Gérald SimonneauHôpital Bicêtre, Université Paris-Sud, Le Kremlin Bicêtre, France.
Olivier SitbonHôpital Bicêtre, Université Paris-Sud, Le Kremlin Bicêtre, France.ORCID https://orcid.org/0000-0002-1942-1951
Victor F TapsonCedars-Sinai Medical Center, Los Angeles, CA, USA.
Nazzareno GalièAlma Mater Studiorum, University of Bologna and IRCCS-S.Orsola University Hospital, Bologna, Italy.
Johnson & Johnson (Switzerland) · CHUniversité Paris-Sud · FRCedars-Sinai Medical Center · USImperial College London · GBJohns Hopkins University · USMater Misericordiae University Hospital · IEMedical University of Vienna · ATMedizinische Hochschule Hannover · DESouthwestern Medical Center · USThe Royal Free Hospital · GBUniversity of Bologna · ITUniversity of California, Los Angeles · USUniversity of Michigan · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Further understanding of when to initiate therapies in pulmonary arterial hypertension (PAH) is important to improve long-term outcomes.

Identifiers

PMID36687361
PMCPMC9841313
OpenAlexW4308708682

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.