Evidence map›Paper›PMID 36687336›Full record

ReviewBiotechnology and bioprocess engineering : BBE2023

The Use of Cell-free Protein Synthesis to Push the Boundaries of Synthetic Biology.

Kyu Jae Kim, So-Jeong Lee, Dong-Myung Kim

Abstract readReview
In one paragraph

Review in Biotechnology and bioprocess engineering : BBE, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Applied and environmental microbiology · 2024
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kyu Jae KimDepartment of Chemical Engineering and Applied Chemistry, Chungnam National University, Daejeon, 34134 Korea.
So-Jeong LeeDepartment of Chemical Engineering and Applied Chemistry, Chungnam National University, Daejeon, 34134 Korea.
Dong-Myung KimDepartment of Chemical Engineering and Applied Chemistry, Chungnam National University, Daejeon, 34134 Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cell-free protein synthesis is emerging as a powerful tool to accelerate the progress of synthetic biology. Notably, cell-free systems that harness extracted synthetic machinery of cells can address many of the issues associated with the complexity and variability of living systems. In particular, cell-free systems can be programmed with various configurations of genetic information, providing great flexibility and accessibility to the field of synthetic biology. Empowered by recent progress, cell-free systems are now evolving into artificial biological systems that can be tailored for various applications, including on-demand biomanufacturing, diagnostics, and new materials design. Here, we review the key developments related to cell-free protein synthesis systems, and discuss the future directions of these promising technologies.

Indexed as

artificial cellscell-free protein synthesismetabolic engineeringrecombinant proteinssynthetic biology

Identifiers

PMID36687336
PMCPMC9840425

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.