Evidence map›Paper›PMID 36687315›Full record

ArticleiScience2023

Monkeypox infection elicits strong antibody and B cell response against A35R and H3L antigens.

Ron Yefet, Nadav Friedel, Hadas Tamir, Ksenia Polonsky, Michael Mor, Lilach Cherry-Mimran, Eyal Taleb, David Hagin, Eli Sprecher, Tomer Israely and 1 more

Open access · goldAbstract read
In one paragraph

Article in iScience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 43 citations in OpenAlex.

  1. Review
  2. Article
  3. Durability of the Humoral Response to MPXV Infection.Journal of the International AIDS Society · 2026
    Review
  4. Article
  5. Article
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  19. Article
  20. Exploring monkeypox virus proteins and rapid detection techniques.Frontiers in cellular and infection microbiology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Ron YefetDepartment of Microbiology and Clinical Immunology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Nadav FriedelDivision of Dermatology, Tel-Aviv Sourasky Medical Center, Tel Aviv, Israel.
Hadas TamirDepartment of Infectious Diseases, The Israel Institute for Biological Research, Ness Ziona, Israel.
Ksenia PolonskyDepartment of Microbiology and Clinical Immunology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Michael MorDepartment of Microbiology and Clinical Immunology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Lilach Cherry-MimranDepartment of Infectious Diseases, The Israel Institute for Biological Research, Ness Ziona, Israel.
Eyal TalebDivision of Dermatology, Tel-Aviv Sourasky Medical Center, Tel Aviv, Israel.
David HaginDepartment of Immunology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Eli SprecherDivision of Dermatology, Tel-Aviv Sourasky Medical Center, Tel Aviv, Israel.
Tomer IsraelyDepartment of Infectious Diseases, The Israel Institute for Biological Research, Ness Ziona, Israel.
Natalia T FreundDepartment of Microbiology and Clinical Immunology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Tel Aviv University · ILIsrael Institute for Biological Research · ILTel Aviv Sourasky Medical Center · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Monkeypox virus (MPXV) resides in two forms; mature and enveloped, and depending on it, distinct proteins are displayed on the viral surface. Here, we expressed two MPXV antigens from the mature, and one from the enveloped form, and tested their reactivity to sera of 11 MPXV recoverees while comparing to sera from recently and past vaccinated individuals. 8 out of 11 recoverees exhibited detectable neutralization levels against Vaccinia Lister. Sera from all recoverees bound strongly to A35R and H3L antigens. Moreover, the responses to A35R were significantly higher within the recoverees compared to both recently and past vaccinated donors. Lastly, A35R- and H3L-specific IgG

Indexed as

Immunological methodsImmunologyVirology

Identifiers

PMID36687315
PMCPMC9838220
OpenAlexW4315864720

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.