Evidence map›Paper›PMID 36686935›Full record

ArticleRSC advances2023

Synthesis and immunopharmacological evaluation of novel TLR7 agonistic triazole tethered imidazoquinolines.

Ayyappa Avoni, Sravanthi Vemireddy, Shainy Sambyal, Syed Shafi, Imran Khan, Aarif Khan, Halmuthur M Sampath Kumar

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Ayyappa AvoniVaccine Immunology Laboratory, OSPC Division, CSIR-Indian Institute of Chemical Technology Hyderabad 500007 India sampath.iict@gov.in +91-40-27160387 +914027191824.
Sravanthi VemireddyVaccine Immunology Laboratory, OSPC Division, CSIR-Indian Institute of Chemical Technology Hyderabad 500007 India sampath.iict@gov.in +91-40-27160387 +914027191824.
Shainy SambyalVaccine Immunology Laboratory, OSPC Division, CSIR-Indian Institute of Chemical Technology Hyderabad 500007 India sampath.iict@gov.in +91-40-27160387 +914027191824.
Syed ShafiDepartment of Chemistry, Hamdard University Hamdard Nagar New Delhi Delhi 110062 India.
Imran KhanDepartment of Chemistry, Hamdard University Hamdard Nagar New Delhi Delhi 110062 India.
Aarif KhanDepartment of Chemistry, Hamdard University Hamdard Nagar New Delhi Delhi 110062 India.
Halmuthur M Sampath KumarVaccine Immunology Laboratory, OSPC Division, CSIR-Indian Institute of Chemical Technology Hyderabad 500007 India sampath.iict@gov.in +91-40-27160387 +914027191824.ORCID https://orcid.org/0000-0002-4473-4220
Indian Institute of Chemical Technology · INJamia Hamdard · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Toll-like receptors-7 and -8 are expressed abundantly on antigen-presenting cells, and their agonists make potential adjuvant candidates for the development of new efficacious vaccines. In view of the importance of new efficacious imidazoquinoline based adjuvants, herein we have synthesized a focused library of a new class of imidazoquinolines retaining the

Identifiers

PMID36686935
PMCPMC9811562
OpenAlexW4313592513

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.