Evidence map›Paper›PMID 36686811›Full record

ArticleFrontiers in oncology2022

Multitasking dynamic contrast enhanced magnetic resonance imaging can accurately differentiate chronic pancreatitis from pancreatic ductal adenocarcinoma.

Nan Wang, Srinivas Gaddam, Yibin Xie, Anthony G Christodoulou, Chaowei Wu, Sen Ma, Zhaoyang Fan, Lixia Wang, Simon Lo, Andrew E Hendifar and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Nan WangBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Srinivas GaddamThe Karsh Division of Gastroenterology and Hepatology, Cedars Sinai Medical Center, Los Angeles, CA, United States.
Yibin XieBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Anthony G ChristodoulouBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Chaowei WuBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Sen MaBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Zhaoyang FanBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Lixia WangBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Simon LoThe Karsh Division of Gastroenterology and Hepatology, Cedars Sinai Medical Center, Los Angeles, CA, United States.
Andrew E HendifarSamuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Stephen J PandolThe Karsh Division of Gastroenterology and Hepatology, Cedars Sinai Medical Center, Los Angeles, CA, United States.
Debiao LiBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States.

Funding

Motion-Resolved, Comprehensive Quantitative Tissue Characterization Using MR MultitaskingR01EB028146 · NIBIB · CEDARS-SINAI MEDICAL CENTER · PI CHRISTODOULOU, ANTHONY G, LI, DEBIAO · 2019 to 2022
$2.5M
Fully Quantitative Low-Dose, Motion-Resolved Dynamic Contrast-Enhanced MRI in Pancreatic AdenocarcinomaR01EB032801 · NIBIB · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Anthony G Christodoulou, Debiao Li · 2022 to 2026
$2.1M
NIBIB NIH HHS R01 EB028146NIBIB NIH HHS R01 EB032801
6 · The paper itself

Abstract

Background and aims: Accurate differentiation of chronic pancreatitis (CP) and pancreatic ductal adenocarcinoma (PDAC) is an area of unmet clinical need. In this study, a novel Multitasking dynamic contrast enhanced (DCE) magnetic resonance imaging (MRI) technique was used to quantitatively evaluate the microcirculation properties of pancreas in CP and PDAC and differentiate between them. Methods: The Multitasking DCE technique was able to acquire one 3D image per second during the passage of MRI contrast agent, allowing the quantitative estimation of microcirculation properties of tissue, including blood flow F Results: Fourteen PDAC patients, 8 CP patients and 20 healthy subjects were prospectively recruited. The combination of F Conclusion: Multitasking DCE MRI is a promising clinical tool that is capable of unbiased quantitative differentiation between CP from PDAC.

Indexed as

differential diagnosis of chronic pancreatitis and pancreatic ductal adenocarcinomadynamic contrast enhanced magnetic resonance imagingmicrocirculation propertiesMultitasking DCEquantitative imaging

Identifiers

PMID36686811
PMCPMC9853434

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.