Evidence map›Paper›PMID 36686668›Full record

ReviewFrontiers in pharmacology2022

An insight into the neuroprotective and anti-neuroinflammatory effects and mechanisms of

Ummi Kalthum Azlan, Nur Aisyah Khairul Annuar, Ahmed Mediani, Wan Mohd Aizat, Hanafi Ahmad Damanhuri, Xiaohui Tong, Daijiro Yanagisawa, Ikuo Tooyama, Wan Zurinah Wan Ngah, Ibrahim Jantan and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
17.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 44 citations in OpenAlex.

  1. FermentedPharmaceutical biology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Therapeutic Potential ofJournal of inflammation research · 2026
    Review
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  7. Article
  8. Article
  9. Article
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  11. Review
  12. Review
  13. Review
  14. Food science & nutrition · 2025
    Article
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  16. Article
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Ummi Kalthum AzlanInstitute of Systems Biology, Universiti Kebangsaan Malaysia, Bangi, Selangor, Malaysia.
Nur Aisyah Khairul AnnuarInstitute of Systems Biology, Universiti Kebangsaan Malaysia, Bangi, Selangor, Malaysia.
Ahmed MedianiInstitute of Systems Biology, Universiti Kebangsaan Malaysia, Bangi, Selangor, Malaysia.
Wan Mohd AizatInstitute of Systems Biology, Universiti Kebangsaan Malaysia, Bangi, Selangor, Malaysia.
Hanafi Ahmad DamanhuriDepartment of Biochemistry, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Center, Kuala Lumpur, Malaysia.
Xiaohui TongSchool of Life Sciences, Anhui University of Chinese Medicine, Hefei, China.
Daijiro YanagisawaMolecular Neuroscience Research Center, Shiga University of Medical Science, Otsu, Japan.
Ikuo TooyamaMedical Innovation Research Center, Shiga University of Medical Science, Otsu, Japan.
Wan Zurinah Wan NgahMedical Innovation Research Center, Shiga University of Medical Science, Otsu, Japan.
Ibrahim JantanInstitute of Systems Biology, Universiti Kebangsaan Malaysia, Bangi, Selangor, Malaysia.
Hamizah Shahirah HamezahInstitute of Systems Biology, Universiti Kebangsaan Malaysia, Bangi, Selangor, Malaysia.
National University of Malaysia · MYShiga University of Medical Science · JPAnhui University of Traditional Chinese Medicine · CNShiga University · JPUniversity Kebangsaan Malaysia Medical Centre · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neurodegenerative diseases (NDs) are sporadic maladies that affect patients' lives with progressive neurological disabilities and reduced quality of life. Neuroinflammation and oxidative reaction are among the pivotal factors for neurodegenerative conditions, contributing to the progression of NDs, such as Parkinson's disease (PD), Alzheimer's disease (AD), multiple sclerosis (MS) and Huntington's disease (HD). Management of NDs is still less than optimum due to its wide range of causative factors and influences, such as lifestyle, genetic variants, and environmental aspects. The neuroprotective and anti-neuroinflammatory activities of

Indexed as

anti-neuroinflammatorymechanismsMoringa oleiferaneurodegenerativeneuropharmacological propertiesphytochemicals

Identifiers

PMID36686668
PMCPMC9849397
OpenAlexW4313574548

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.