Evidence map›Paper›PMID 36686665›Full record

ArticleFrontiers in pharmacology2022

A novel nomogram and prognostic factor for metastatic renal cell carcinoma survival in the era of immune checkpoint inhibitors (ICIs).

Mohammed Alradhi, Zewen Zhang, Mohammed Safi, Abdullah Al-Danakh, Mokhtar Aldhbi, Salim Baldi, Li Kui, Abdulaziz Alradhi, Saeed Bin Hamri, Ka Lun Lo and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Life Factors and Melanoma: From the Macroscopic State to the Molecular Mechanism.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 10 institutions in 3 countries.

Mohammed AlradhiDepartment of Urology, The Affiliated Hospital of Qingdao Binhai Univesity, Qingdao, China.
Zewen ZhangDepartment of Radiology, Jinan Central Hospital Affiliated to Shandong First Medical University, Jinan, China.
Mohammed SafiDepartment of Respiratory Diseases, Shandong Second Provincial General Hospital, Shandong University, Jinan, China.
Abdullah Al-DanakhDepartment of Urology, First Affiliated Hospital of Dalian Medical University, Dalian, China.
Mokhtar AldhbiDepartment of Urology, The Affiliated Hospital of Qingdao Binhai Univesity, Qingdao, China.
Salim BaldiResearch Center of Molecular Diagnostics and Sequencing, Axbio Biotechnology (Shenzhen) Co., Ltd., Shenzhen, China.
Li KuiDepartment of Urology, The Affiliated Hospital of Qingdao Binhai Univesity, Qingdao, China.
Abdulaziz AlradhiDepartment of Thoracic Surgery, Prince Mutaib Bin Abdulaziz Hospital, Al-jawf, Saudi Arabia.
Saeed Bin HamriDivision of Urology, Department of Surgery, Ministry of the National Guard Health Affairs, Riyadh, Saudi Arabia.
Ka Lun LoDivision of Urology, Department of Surgery, The Chinese University of Hong Kong, Hong Kong, Hong Kong SAR, China.
Yi ZhaoDepartment of Oncology, First Affiliated Hospital of Dalian Medical University, Dalian, China.
Yang JinDepartment of Urology, The Affiliated Hospital of Qingdao Binhai Univesity, Qingdao, China.
Affiliated Hospital of Qingdao University · CNAmran University · YEChinese University of Hong Kong · CNDalian Medical University · CNFirst Affiliated Hospital of Dalian Medical University · CNJinan Central Hospital · CNNational Guard Health Affairs · SAPrince Mohammed bin Abdulaziz Hospital · SAQingdao University · CNState Key Laboratory of Respiratory Disease · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with metastatic renal cell cancer (mRCC) for whom surgery is ineffective may experience a poor prognosis. The different sites where cancer has spread, and the different ways to treat it in the immune checkpoint inhibitors era could help clinical decision-making. In this study, individuals with mRCC were selected from the SEER database between 2015 and 2016 based on the Food and Drug Administration (FDA) approval of ICIs. A total of 4011 mRCC patients were studied (2239 with lung metastasis vs. 797 with liver metastasis in the immune checkpoint inhibitors period). The age

Indexed as

immune checkpoint inhibitors (ICI)metastatic renal cell carcinomanomogramSEERsurvival

Identifiers

PMID36686665
PMCPMC9846485
OpenAlexW4313585104

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.