Evidence map›Paper›PMID 36686571›Full record

ArticleGastroenterology report2023

Artificial intelligence empowers the second-observer strategy for colonoscopy: a randomized clinical trial.

Pu Wang, Xiao-Gang Liu, Min Kang, Xue Peng, Mei-Ling Shu, Guan-Yu Zhou, Pei-Xi Liu, Fei Xiong, Ming-Ming Deng, Hong-Fen Xia and 4 more

Open access · diamondAbstract read
In one paragraph

Article in Gastroenterology report, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
2.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.

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  8. [Role of Artificial Intelligence in Improving Quality of Colonoscopy].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Pu WangDepartment of Gastroenterology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan, P. R. China.ORCID https://orcid.org/0000-0002-1234-309X
Xiao-Gang LiuDepartment of Gastroenterology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan, P. R. China.
Min KangDepartment of Gastroenterology, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, P. R. China.
Xue PengDepartment of Gastroenterology, Xinqiao Hospital, Third Military Medical University, Chongqing, P. R. China.
Mei-Ling ShuDepartment of Gastroenterology, Suining Central Hospital, Suining, Sichuan, P. R. China.
Guan-Yu ZhouDepartment of Gastroenterology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan, P. R. China.
Pei-Xi LiuDepartment of Gastroenterology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan, P. R. China.
Fei XiongDepartment of Gastroenterology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan, P. R. China.
Ming-Ming DengDepartment of Gastroenterology, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, P. R. China.
Hong-Fen XiaDepartment of Gastroenterology, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, P. R. China.
Jian-Jun LiDepartment of Gastroenterology, Xinqiao Hospital, Third Military Medical University, Chongqing, P. R. China.
Xiao-Qi LongDepartment of Gastroenterology, Suining Central Hospital, Suining, Sichuan, P. R. China.
Yan SongDepartment of Gastroenterology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan, P. R. China.
Liang-Ping LiDepartment of Gastroenterology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan, P. R. China.
University of Electronic Science and Technology of China · CNAffiliated Hospital of Southwest Medical University · CNArmy Medical University · CNSuizhou Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In colonoscopy screening for colorectal cancer, human vision limitations may lead to higher miss rate of lesions; artificial intelligence (AI) assistance has been demonstrated to improve polyp detection. However, there still lacks direct evidence to demonstrate whether AI is superior to trainees or experienced nurses as a second observer to increase adenoma detection during colonoscopy. In this study, we aimed to compare the effectiveness of assistance from AI and human observer during colonoscopy. Methods: A prospective multicenter randomized study was conducted from 2 September 2019 to 29 May 2020 at four endoscopy centers in China. Eligible patients were randomized to either computer-aided detection (CADe)-assisted group or observer-assisted group. The primary outcome was adenoma per colonoscopy (APC). Secondary outcomes included polyp per colonoscopy (PPC), adenoma detection rate (ADR), and polyp detection rate (PDR). We compared continuous variables and categorical variables by using R studio (version 3.4.4). Results: A total of 1,261 (636 in the CADe-assisted group and 625 in the observer-assisted group) eligible patients were analysed. APC (0.42 vs 0.35, Conclusions: Compared with the human observer, the CADe system may improve the clinical outcome of colonoscopy and reduce disturbance to routine practice (Chictr.org.cn No.: ChiCTR1900025235).

Indexed as

adenomaartificial intelligencecolon cancer screeningcomputer-aided detectionearly detection

Identifiers

PMID36686571
PMCPMC9850273
OpenAlexW4317780939

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.