Evidence map›Paper›PMID 36686527›Full record

ReviewFrontiers in neurology2022

Autonomic dysfunction in epilepsy mouse models with implications for SUDEP research.

Jennifer Bauer, Orrin Devinsky, Markus Rothermel, Henner Koch

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Electrocardiographic abnormalities in epilepsy: analysis of cardiac conduction patterns and SUDEP Risk.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Pooled it
  2. In-depth characterization of the CaScientific reports · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Jennifer BauerDepartment of Epileptology and Neurology, RWTH Aachen University, Aachen, Germany.
Orrin DevinskyDepartments of Neurology, Neurosurgery and Psychiatry, NYU Langone School of Medicine, New York, NY, United States.
Markus RothermelInstitute for Physiology and Cell Biology, University of Veterinary Medicine Hannover, Foundation, Hannover, Germany.
Henner KochDepartment of Epileptology and Neurology, RWTH Aachen University, Aachen, Germany.
RWTH Aachen University · DENew York University · USUniversity of Veterinary Medicine Hannover, Foundation · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epilepsy has a high prevalence and can severely impair quality of life and increase the risk of premature death. Sudden unexpected death in epilepsy (SUDEP) is the leading cause of death in drug-resistant epilepsy and most often results from respiratory and cardiac impairments due to brainstem dysfunction. Epileptic activity can spread widely, influencing neuronal activity in regions outside the epileptic network. The brainstem controls cardiorespiratory activity and arousal and reciprocally connects to cortical, diencephalic, and spinal cord areas. Epileptic activity can propagate trans-synaptically or

Indexed as

brainstemcardiorespiratory activityepilepsymouse modelsSUDEP

Identifiers

PMID36686527
PMCPMC9853197
OpenAlexW4313650422

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.