Evidence map›Paper›PMID 36686501›Full record

ArticleFrontiers in neurology2022

Quality of life: Seasonal fluctuation in Parkinson's disease.

Lei Wu, Shiyu Li, Yilin Tang, Xiaoniu Liang, Zhiheng Xu, Tianyu Hu, Xiaoli Liu, Miao Cai, Xuedong Liu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lei WuDepartment of Neurology, The First Affiliated Hospital, Sun Yat-sen University; Guangdong Provincial Key Laboratory of Diagnosis and Treatment of Major Neurological Diseases; National Key Clinical Department and Key Discipline of Neurology, Guangzhou, China.
Shiyu LiState Key Laboratory of Medical Neurobiology, Department of Neurology, Huashan Hospital, National Research Center for Aging and Medicine and National Center for Neurological Disorders, Fudan University, Shanghai, China.
Yilin TangState Key Laboratory of Medical Neurobiology, Department of Neurology, Huashan Hospital, National Research Center for Aging and Medicine and National Center for Neurological Disorders, Fudan University, Shanghai, China.
Xiaoniu LiangState Key Laboratory of Medical Neurobiology, Department of Neurology, Huashan Hospital, National Research Center for Aging and Medicine and National Center for Neurological Disorders, Fudan University, Shanghai, China.
Zhiheng XuState Key Laboratory of Medical Neurobiology, Department of Neurology, Huashan Hospital, National Research Center for Aging and Medicine and National Center for Neurological Disorders, Fudan University, Shanghai, China.
Tianyu HuState Key Laboratory of Medical Neurobiology, Department of Neurology, Huashan Hospital, National Research Center for Aging and Medicine and National Center for Neurological Disorders, Fudan University, Shanghai, China.
Xiaoli LiuDepartment of Neurology, Zhejiang Hospital, Hangzhou, China.
Miao CaiDepartment of Neurology, Zhejiang Hospital, Hangzhou, China.
Xuedong LiuDepartment of Neurology, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Although the seasonal variation of motor and non-motor symptoms in Parkinson's disease (PD) has been reported, the association between seasonal change and quality of life in patients with Parkinson's disease remains to be explored. Methods: We recruited 1,036 patients with PD in this cross-sectional retrospective study. The patients were divided into four groups based on their date of assessment, according to the classical four seasons: group 1: March to May ( Results: A significant difference in PDQ-39 was found between group 1 (spring months) and group 3 (autumn months) after correction ( Interpretation: The current study reported seasonal fluctuation of QoL in patients with PD, with higher scores during the spring months and lower scores in the autumn months. Since the determinants for QoL also vary by season, clinicians might need to focus on specific factors across seasons before initiating therapy.

Indexed as

determinantsepidemiologic factorsParkinson's diseasequality of lifeseasons

Identifiers

PMID36686501
PMCPMC9846796

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.