Evidence map›Paper›PMID 36686478›Full record

SynthesisFrontiers in endocrinology2022

Role of paraspinal muscle degeneration in the occurrence and recurrence of osteoporotic vertebral fracture: A meta-analysis.

Zhi Chen, Tengbin Shi, Wenwen Li, Jun Sun, Zhipeng Yao, Wenge Liu

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Osteosarcopenia and vertebral fracture burden: toward integrated musculoskeletal risk assessment.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Article
  7. Article
  8. Review
  9. Article
  10. Observational
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. [Osteoporotic vertebral body fractures].Orthopadie (Heidelberg, Germany) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Zhi ChenDepartment of Orthopedic Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian, China.
Tengbin ShiDepartment of Orthopedic Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian, China.
Wenwen LiThe School of Health, Fujian Medical University, Fuzhou, Fujian, China.
Jun SunDepartment of Emergency, Zhaotong Traditional Chinese Medicine Hospital, Zhaotong, Yunnan, China.
Zhipeng YaoDepartment of Orthopedic Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian, China.
Wenge LiuDepartment of Orthopedic Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian, China.
Fujian Medical University · CNUnion Hospital · CNJining Traditional Chinese Medicine Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Recently, the effects of paraspinal muscle degeneration on osteoporotic vertebral fractures (OVFs) have attracted the attention of researchers; however, studies are limited, and their results vary. Hence, this study aimed to determine the role of paraspinal muscle degeneration in the occurrence and recurrence of OVF. Methods: Following the preferred reporting items for systematic reviews and meta-analysis (PRISMA) guideline, the PubMed, Embase, Web of Science, Wanfang Data, China National Knowledge Infrastructure, and ClinicalTrials.gov databases were comprehensively searched for relevant studies. Studies comparing the cross-sectional area (CSA) or fatty infiltration (FI) of the paraspinal muscles (including the psoas (PS), erector spinae plus multifidus (ES+MF), quadratus lumborum) in patients with and without initial OVF, or with and without recurrent OVF were included and analyzed. Results: Eleven studies were included in the meta-analysis. Seven studies investigated the effects of paraspinal muscles on initial OVF, and the overall results revealed significantly lower CSA Conclusions: Paraspinal muscle degeneration plays a role in the occurrence and recurrence of OVF. Assessing the paraspinal muscles may be useful for identifying high-risk populations. Systematic Review Registration: https://www.crd.york.ac.uk/prospero/, identifier (CRD42021276681).

Indexed as

Osteoporotic FracturesSpinal FracturesHumansLumbar VertebraeMagnetic Resonance ImagingMuscular AtrophyParaspinal MusclesRetrospective Studiesdegenerationmeta-analysisosteoporotic vertebral compression fractureparaspinal musclesrefracture

Identifiers

PMID36686478
PMCPMC9845601
OpenAlexW4313585755

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.