Evidence map›Paper›PMID 36686460›Full record

ArticleFrontiers in endocrinology2022

Genetic polymorphisms of Ca

Zongzhe Tang, Yajie Ding, Ru Zhang, Mengting Zhang, Qing Guan, Liuxin Zhang, Hongliang Wang, Yue Chen, Rong Jiang, Wei Zhang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Zongzhe TangDepartment of Fundamental and Community Nursing, School of Nursing, Nanjing Medical University, Nanjing, China.
Yajie DingDepartment of Fundamental and Community Nursing, School of Nursing, Nanjing Medical University, Nanjing, China.
Ru ZhangDepartment of Fundamental and Community Nursing, School of Nursing, Nanjing Medical University, Nanjing, China.
Mengting ZhangDepartment of Fundamental and Community Nursing, School of Nursing, Nanjing Medical University, Nanjing, China.
Qing GuanDepartment of Fundamental and Community Nursing, School of Nursing, Nanjing Medical University, Nanjing, China.
Liuxin ZhangDepartment of Neurosurgery, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, China.
Hongliang WangDepartment of General Practice, Ninghai Road Community Health Service Center, Nanjing, China.
Yue ChenDepartment of Fundamental and Community Nursing, School of Nursing, Nanjing Medical University, Nanjing, China.
Rong JiangDepartment of Fundamental and Community Nursing, School of Nursing, Nanjing Medical University, Nanjing, China.
Wei ZhangDepartment of Epidemiology, Shanghai Cancer Institute, Shanghai, China.
Jie WangDepartment of Fundamental and Community Nursing, School of Nursing, Nanjing Medical University, Nanjing, China.
Nanjing Medical University · CNNanjing Brain Hospital · CNNinghai First Hospital Medicare and Health Group · CNShanghai Cancer Institute · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Non-alcoholic fatty liver disease (NAFLD) is recognized to be closely associated with endoplasmic reticulum stress and mitochondrial dysfunction, while previous studies have emphasized the important role of calcium homeostasis from the mitochondria-associated endoplasmic reticulum membrane (MAM) in the endoplasmic reticulum and mitochondria. This article will assess the association between genetic polymorphisms of Ca Methods: A case-control study was conducted in a community of Nanjing, China during April to December 2020. 2701 subjects were enrolled and genotyped for 6 genetic variants in Results: After adjusting for age, gender, total cholesterol and glucose, we identified that Conclusion: The variant genotypes of Ca

Indexed as

Non-alcoholic Fatty Liver DiseaseCarrier ProteinsCase-Control StudiesEndoplasmic ReticulumGenetic Predisposition to DiseaseHumansMitochondriaMolecular ChaperonesPolymorphism, Single NucleotideCarrier ProteinsMolecular Chaperonescalcium homeostasisgenetic polymorphismheat shock 70-kDa protein 5 (HSPA5)inositol 1,4,5-trisphosphate receptor type 2 (ITPR2)non-alcoholic fatty liver disease (NAFLD)

Identifiers

PMID36686460
PMCPMC9846251
OpenAlexW4313586264

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.