Evidence map›Paper›PMID 36686258›Full record

ArticleFrontiers in bioengineering and biotechnology2022

Whole transcriptomic analysis of mesenchymal stem cells cultured in Nichoid micro-scaffolds.

Carolina Testa, Stefania Oliveto, Emanuela Jacchetti, Francesca Donnaloja, Chiara Martinelli, Pietro Pinoli, Roberto Osellame, Giulio Cerullo, Stefano Ceri, Stefano Biffo and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Adaptation of mesenchymal stromal cells to culture on collagen-based bioscaffold.Journal of materials science. Materials in medicine · 2026
    Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Carolina TestaDepartment of Electronics, Information and Bioengineering, Politecnico di Milano, Milano, Italy.
Stefania OlivetoDepartment of Bioscience (DBS), University of Milan, Milano, Italy.
Emanuela JacchettiDepartment of Chemistry, Materials and Chemical Engineering "Giulio Natta", Politecnico di Milano, Milano, Italy.
Francesca DonnalojaDepartment of Chemistry, Materials and Chemical Engineering "Giulio Natta", Politecnico di Milano, Milano, Italy.
Chiara MartinelliDepartment of Chemistry, Materials and Chemical Engineering "Giulio Natta", Politecnico di Milano, Milano, Italy.
Pietro PinoliDepartment of Electronics, Information and Bioengineering, Politecnico di Milano, Milano, Italy.
Roberto OsellameInstitute of Photonics and Nanotechnology (IFN)-CNR and Department of Physics, Politecnico di Milano, Milano, Italy.
Giulio CerulloInstitute of Photonics and Nanotechnology (IFN)-CNR and Department of Physics, Politecnico di Milano, Milano, Italy.
Stefano CeriDepartment of Electronics, Information and Bioengineering, Politecnico di Milano, Milano, Italy.
Stefano BiffoDepartment of Bioscience (DBS), University of Milan, Milano, Italy.
Manuela T RaimondiDepartment of Chemistry, Materials and Chemical Engineering "Giulio Natta", Politecnico di Milano, Milano, Italy.
Politecnico di Milano · ITUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mesenchymal stem cells (MSCs) are known to be ideal candidates for clinical applications where not only regenerative potential but also immunomodulation ability is fundamental. Over the last years, increasing efforts have been put into the design and fabrication of 3D synthetic niches, conceived to emulate the native tissue microenvironment and aiming at efficiently controlling the MSC phenotype

Indexed as

3D cell culturebioengineering, immunemodulationcell adhesion moleculesmechanobiologymesenchymal stem cellsnichesynthetictranscriptomic analysis

Identifiers

PMID36686258
PMCPMC9852851
OpenAlexW4313645412

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.