Evidence map›Paper›PMID 36686152›Full record

ArticleAdvanced photonics research2022

Bioimaging with Upconversion Nanoparticles.

Evan M Mettenbrink, Wen Yang, Stefan Wilhelm

Abstract read
In one paragraph

Article in Advanced photonics research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Closing the Loop: High-Precision 3D Photofabrication in Living Tissues.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. YbAngewandte Chemie (International ed. in English) · 2026
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. NIR-Excited Imaging of Cervical Cancer Cells Using Biocompatible LaFLuminescence : the journal of biological and chemical luminescence · 2025
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Photon Upconversion of Defect-Bound Excitons in hBN-Encapsulated MoSThe journal of physical chemistry. C, Nanomaterials and interfaces · 2024
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Evan M MettenbrinkStephenson School of Biomedical Engineering, University of Oklahoma, Norman, Oklahoma, 73019, USA.ORCID 0000-0002-1130-2907
Wen YangStephenson School of Biomedical Engineering, University of Oklahoma, Norman, Oklahoma, 73019, USA.
Stefan WilhelmStephenson School of Biomedical Engineering, University of Oklahoma, Norman, Oklahoma, 73019, USA.ORCID 0000-0003-2167-6221

Funding

Use of 3D Quantitative Optical Methods to Optimize Mebendazole Treatment of Ovarian CancerP20GM135009 · NIGMS · UNIVERSITY OF OKLAHOMA · PI Yuye Ling · 2022 to 2026
$13.6M
NIGMS NIH HHS P20 GM135009
6 · The paper itself

Abstract

Bioimaging enables the spatiotemporal visualization of biological processes at various scales empowered by a range of different imaging modalities and contrast agents. Upconversion nanoparticles (UCNPs) represent a distinct type of such contrast agents with the potential to transform bioimaging due to their unique optical properties and functional design flexibilities. This review explores and discusses the opportunities, challenges, and limitations that UCNPs exhibit as bioimaging probes and highlights applications with spatial dimensions ranging from the single nanoparticle level to cellular, tissue, and whole animal imaging. We further summarized recent advancements in bioimaging applications enabled by UCNPs, including super-resolution techniques and multimodal imaging methods, and provide a perspective on the future potential of UCNP-based technologies in bioimaging research and clinical translation. This review may provide a valuable resource for researchers interested in exploring and applying UCNP-based bioimaging technologies.

Indexed as

bioimagingin vivo imagingluminescencemicroscopymultimodalnanoparticlessuper-resolutionUpconversion

Identifiers

PMID36686152
PMCPMC9858112

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.