Evidence map›Paper›PMID 36685998›Full record

ArticlePostepy dermatologii i alergologii2022

Bronchodilator response after two methods of salbutamol nebulization in asthmatic children.

Andrzej Emeryk, Kamil Janeczek, Ewa Markut-Miotła, Michał Pirożyński, Emil Florkiewicz

Open access · goldAbstract read
In one paragraph

Article in Postepy dermatologii i alergologii, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Andrzej EmerykDepartment of Pulmonary Diseases and Children Rheumatology, Medical University of Lublin, Lublin, Poland.
Kamil JaneczekDepartment of Pulmonary Diseases and Children Rheumatology, Medical University of Lublin, Lublin, Poland.
Ewa Markut-MiotłaDepartment of Pulmonary Diseases and Children Rheumatology, Medical University of Lublin, Lublin, Poland.
Michał PirożyńskiCentre of Allergology, Pneumonology and Emergency Medicine - Simulation Centre, Centre of Postgraduate Medical Education, Warsaw, Poland.
Emil FlorkiewiczNon-public Medical Centre ESKULAP, Sieradz, Poland.
Medical University of Lublin · PLPostgraduate School of Molecular Medicine · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Salbutamol is used in bronchodilator response testing (BDRT), which is an important diagnostic tool in bronchial obstructive diseases. Most available studies compare the bronchodilator response of salbutamol administered with a pressurized metered-dose inhaler and salbutamol in a nebulization solution. Aim: The spirometric evaluation of the bronchodilator response of two methods of salbutamol nebulization in asthmatic children. Material and methods: A randomized, open, comparative study was conducted in which 132 children with partially controlled asthma and current bronchial obstruction determined by spirometry were enrolled. BDRT was conducted using salbutamol solution administered with either a continuous jet nebulizer (CON) or a breath-actuated jet nebulizer (BAN). The BAN group received half the dose of the drug compared to the CON group, i.e. 2.5 mg. Changes in FEV Results: The change in FEV Conclusions: Salbutamol inhaled from BAN results in a better bronchodilator response than twice the nominal dose of this drug inhaled from CON, which is due to the absence of drug loss during the expiratory phase and therefore greater pulmonary deposition.

Indexed as

asthmabronchodilator responsechildrennebulizationsalbutamol

Identifiers

PMID36685998
PMCPMC9837600
OpenAlexW4285060146

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.