Evidence map›Paper›PMID 36685830›Full record

ReviewFrontiers in genetics2022

Circular RNAs in extracellular vesicles: Promising candidate biomarkers for schizophrenia.

Chuang Guo, Haibing Lv, Yulong Bai, Meng Guo, Pengfei Li, Shuping Tong, Kuanjun He

Abstract readReview
In one paragraph

Review in Frontiers in genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Microorganisms · 2025
    Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Biomarkers in schizophrenia - past, present and future.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chuang GuoCollege of Life Sciences and Food Engineering, Inner Mongolia Minzu University, Tongliao, China.
Haibing LvCollege of Life Sciences and Food Engineering, Inner Mongolia Minzu University, Tongliao, China.
Yulong BaiCollege of Life Sciences and Food Engineering, Inner Mongolia Minzu University, Tongliao, China.
Meng GuoNetwork Center, Inner Mongolia Minzu University, Tongliao, China.
Pengfei LiAffiliated Hospital of Inner Mongolia Minzu University, Tongliao, China.
Shuping TongAffiliated Hospital of Inner Mongolia Minzu University, Tongliao, China.
Kuanjun HeCollege of Life Sciences and Food Engineering, Inner Mongolia Minzu University, Tongliao, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As one of common and severe mental illnesses, schizophrenia is difficult to be diagnosed exactly. Both its pathogenesis and the causes of its development are still uncertain because of its etiology complexity. At present, the diagnosis of schizophrenia is mainly based on the patient's symptoms and signs, lacking reliable biomarkers that can be used for diagnosis. Circular RNAs in extracellular vesicles (EV circRNAs) can be used as promising candidate biomarkers for schizophrenia and other diseases, for they are not only high stability and disease specificity, but also are rich in contents and easy to be detected. The review is to focus on the research progress of the correlation between circRNAs and schizophrenia, and then to explores the possibility of EV circRNAs as new biomarkers for the schizophrenia diagnosis.

Indexed as

biomarkerscircular RNAsextracellular vesiclesresearch progressschizophrenia

Identifiers

PMID36685830
PMCPMC9852742

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.