Evidence map›Paper›PMID 36685784›Full record

ArticleColloids and surfaces. A, Physicochemical and engineering aspects2022

Modifying surface charge density of thermoplastic nanofluidic biosensors by multivalent cations within the slip plane of the electric double layer.

Zheng Jia, Junseo Choi, Sunggun Lee, Steven A Soper, Sunggook Park

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Colloids and surfaces. A, Physicochemical and engineering aspects, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zheng JiaMechanical & Industrial Engineering Department, Louisiana State University, Baton Rouge, LA 70803, USA.
Junseo ChoiMechanical & Industrial Engineering Department, Louisiana State University, Baton Rouge, LA 70803, USA.
Sunggun LeeMechanical & Industrial Engineering Department, Louisiana State University, Baton Rouge, LA 70803, USA.
Steven A SoperDepartment of Chemistry, University of Kansas, Lawrence, KS 66047, USA.
Sunggook ParkMechanical & Industrial Engineering Department, Louisiana State University, Baton Rouge, LA 70803, USA.

Funding

Using Integrated Omics to Identify Dysfunctional Genetic Mechanisms Influencing Schizophrenia and Sleep DisturbancesP20GM130423 · NIGMS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI ANDREW K. GODWIN · 2019 to 2026
$21.5M
Single-Molecule Processing: Detection and Identification of Single DNAs, RNAs, and Proteins using Immobilized Nanoscale Enzymatic Reactors (INERs) and Nanoscale ElectrophoresisP41EB020594 · NIBIB · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Adam Roger Hall · 2015 to 2026
$15.2M
NIBIB NIH HHS P41 EB020594NIGMS NIH HHS P20 GM130423
6 · The paper itself

Abstract

Thermoplastic nanofluidic devices are promising platforms for sensing single biomolecules due to their mass fabrication capability. When the molecules are driven electrokinetically through nanofluidic networks, surface charges play a significant role in the molecular capture and transportation, especially when the thickness of the electrical double layer is close to the dimensions of the nanostructures in the device. Here, we used multivalent cations to alter the surface charge density of thermoplastic nanofluidic devices. The surface charge alteration was done by filling the device with a multivalent ionic solution, followed by withdrawal of the solution and replacing it with KCl for conductance measurement. A systematic study was performed using ionic solutions containing Mg

Indexed as

Biomolecule sensingCharge inversionDNA translocationMultivalent ionsNanoporeThermoplastic nanofluidics

Identifiers

PMID36685784
PMCPMC9853209

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.