ReviewCurrent research in neurobiology2022
Brain-heart interactions in the neurobiology of consciousness.
Review in Current research in neurobiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
36 citing papers in PubMed, 85 citations in OpenAlex.
- Heartbeat-evoked potentials reveal interoceptive dysfunction in clinical disorders: Experimental frameworks and promising applications.Psychological medicine · 2026Review
- Long-term HRV metrics may assist in differentiating between prolonged disorders of consciousness and emergence from minimally conscious state : a cross-sectional study.Acta neurologica Belgica · 2026Article
- Brain-heart interactions in late-onset major depressive disorder revealed by multimodal HRV-driven fMRI.Communications biology · 2026Article
- Respiratory Variability in Disorders of Consciousness: Relationship and Clinical Applications.CNS neuroscience & therapeutics · 2026Article
- Plant emotion revisited: toward a new conceptual framework.Protoplasma · 2026Review
- Bidirectional brain-heart interactions in health and disease.Nature reviews. Neurology · 2026Review
- NEVi: Negative Emotional Video dataset - categorizing stimulus intensity ratings based on valence and arousal.Scientific data · 2026Article
- The brain and heart-axis in neurodegeneration and cardiovascular disease.Journal of neural transmission (Vienna, Austria : 1996) · 2026Review
- Modulation of the serotonergic system restores oxidative balance and gene expression in the brain and heart of rats with obesity induced by overnutrition.Frontiers in physiology · 2026Article
- I sync, therefore I am: brain-body synchrony in typical and disordered consciousness.Neuroscience of consciousness · 2026Review
- Brain-heart coupling in tourette syndrome: a precision functional mapping study of discordant siblings.Frontiers in network physiology · 2026Article
- Cardiac-vagal rhythm echoes on the heartbeat's mechanosensory imprint in the brain.Communications biology · 2025Article
- Brain activation and heart rate variability as markers of autonomic function under stress.Scientific reports · 2025Article
- Interplay Between Cortical and Neurocardiac Interoceptive Processes and its Association with Self-Reported Interoceptive Sensibility.Brain topography · 2025Article
- Advanced and long-term meditation and the autonomic nervous system: A review and synthesis.Neuroscience and biobehavioral reviews · 2025Review
- Cardiac signals inform auditory regularity processing in the absence of consciousness.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Central Thalamic Deep Brain Stimulation Modulates Autonomic Nervous System Responsiveness in Disorders of Consciousness.CNS neuroscience & therapeutics · 2025Article
- Linking heartbeats with the cortical network dynamics involved in self-social touch distinction.Communications biology · 2025Article
- Brain-body interactions associated with the transition from mind wandering to awareness of its occurrence.Neuroscience of consciousness · 2025Article
- Interoception, cardiac health, and heart failure: The potential for artificial intelligence (AI)-driven diagnosis and treatment.Physiological reports · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent experimental evidence on patients with disorders of consciousness revealed that observing brain-heart interactions helps to detect residual consciousness, even in patients with absence of behavioral signs of consciousness. Those findings support hypotheses suggesting that visceral activity is involved in the neurobiology of consciousness, and sum to the existing evidence in healthy participants in which the neural responses to heartbeats reveal perceptual and self-consciousness. More evidence obtained through mathematical modeling of physiological dynamics revealed that emotion processing is prompted by an initial modulation from ascending vagal inputs to the brain, followed by sustained bidirectional brain-heart interactions. Those findings support long-lasting hypotheses on the causal role of bodily activity in emotions, feelings, and potentially consciousness. In this paper, the theoretical landscape on the potential role of heartbeats in cognition and consciousness is reviewed, as well as the experimental evidence supporting these hypotheses. I advocate for methodological developments on the estimation of brain-heart interactions to uncover the role of cardiac inputs in the origin, levels, and contents of consciousness. The ongoing evidence depicts interactions further than the cortical responses evoked by each heartbeat, suggesting the potential presence of non-linear, complex, and bidirectional communication between brain and heartbeat dynamics. Further developments on methodologies to analyze brain-heart interactions may contribute to a better understanding of the physiological dynamics involved in homeostatic-allostatic control, cognitive functions, and consciousness.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.