Evidence map›Paper›PMID 36685138›Full record

ArticleJournal of cancer science and clinical therapeutics2022

Rapidly Progressive Paraneoplastic Neuropathy Associated with Renal Cell Carcinoma: A Case Report.

Divya Shah, Jaya Trivedi, Steven Vernino, Shaida Khan

Open access · diamondAbstract read
In one paragraph

Article in Journal of cancer science and clinical therapeutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Divya ShahDepartment of Neurology, UT Southwestern Medical Center, Dallas, TX, USA.
Jaya TrivediDepartment of Neurology, UT Southwestern Medical Center, Dallas, TX, USA.
Steven VerninoDepartment of Neurology, UT Southwestern Medical Center, Dallas, TX, USA.
Shaida KhanDepartment of Neurology, UT Southwestern Medical Center, Dallas, TX, USA.
Southwestern Medical CenterSouthwestern Medical Center · US

Funding

EXPERIMENTAL AUTOIMMUNE AUTONOMIC NEUROPATHYK08NS002247 · NINDS · UNIVERSITY OF TEXAS SW MED CTR/DALLAS · PI VERNINO, STEVEN A · 2001 to 2005
$654k
Experimental Dysautonomia: Pathogenesis and TreatmentR01NS048077 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI VERNINO, STEVEN A · 2004 to 2006
$630k
UT Southwestern Integrated Program for the Advancement of Neuroscience Research CareersR25NS098987 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI DIAMOND, MARC I, VERNINO, STEVEN A · 2017 to 2023
$436k
NINDS NIH HHS K08 NS002247NINDS NIH HHS R01 NS048077NINDS NIH HHS R25 NS098987
6 · The paper itself

Abstract

Background: Paraneoplastic neurological disorders are rare syndromes that occur with various malignancies including renal cell carcinoma. Symptoms of paraneoplastic neurological disorders are diverse and involve either the central nervous system, peripheral nervous system, or both. Case Presentation: We present a patient with diffuse limb pain, rapidly progressive asymmetric motor and sensory symptoms and distal upper limb atrophy. Electrodiagnostic testing was suggestive of mononeuritis multiplex. Initial empiric treatment with corticosteroids did not lead to improvement. Further diagnostic studies revealed bilateral clear cell renal carcinoma. Treatment with plasmapheresis led to significant and rapid improvement in pain and limb strength. Conclusions: This case highlights the rare occurrence of paraneoplastic neuropathy in renal cancer and emphasizes the importance of screening for malignancy in patients presenting with rapidly progressive multifocal neuropathy.

Indexed as

Case ReportNeuropathyParaneoplasticPlasmapheresisRenal Cancer

Identifiers

PMID36685138
PMCPMC9851384
OpenAlexW4300935096

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.