Evidence map›Paper›PMID 36684722›Full record

ArticleFrontiers in plant science2022

A metabolomic platform to identify and quantify polyphenols in coffee and related species using liquid chromatography mass spectrometry.

Fernanda R Castro-Moretti, Jean-Christophe Cocuron, Humberto Castillo-Gonzalez, Efrain Escudero-Leyva, Priscila Chaverri, Oliveiro Guerreiro-Filho, Jason C Slot, Ana Paula Alonso

Open access · goldAbstract read
In one paragraph

Article in Frontiers in plant science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Fernanda R Castro-MorettiBioDiscovery Institute and Department of Biological Sciences, University of North Texas, Denton, TX, United States.
Jean-Christophe CocuronBioAnalytical Facility, University of North Texas, Denton, TX, United States.
Humberto Castillo-GonzalezDepartment of Plant Science and Landscape Architecture, University of Maryland, College Park, MD, United States.
Efrain Escudero-LeyvaSchool of Biology and Natural Products Research Center Centro de Investigaciones en Productos Naturales (CIPRONA), University of Costa Rica, San Jose, Costa Rica.
Priscila ChaverriDepartment of Plant Science and Landscape Architecture, University of Maryland, College Park, MD, United States.
Oliveiro Guerreiro-FilhoCoffee Center Agronomic Institute, Campinas, Sao Paulo, Brazil.
Jason C SlotDepartment of Plant Pathology, The Ohio State University, Columbus, OH, United States.
Ana Paula AlonsoBioDiscovery Institute and Department of Biological Sciences, University of North Texas, Denton, TX, United States.
University of North Texas · USUniversity of Maryland, College Park · USAgronomical Institute of Campinas · BRThe Ohio State University · USUniversidad de Costa Rica · CR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Products of plant secondary metabolism, such as phenolic compounds, flavonoids, alkaloids, and hormones, play an important role in plant growth, development, stress resistance. The plant family Methods: First, a method was optimized to extract over 40 families of phytochemicals. Then, a high-throughput metabolomic platform has been developed to identify and quantify 184 polyphenols in 15 min. Results: The current metabolomics study of secondary metabolites was conducted on leaves from one commercial coffee variety and two wild species that also belong to the Discussion: Caffeine, trigonelline and theobromine were highly abundant in coffee leaves, as expected. Interestingly, wild

Indexed as

LC-MS/MSphenolicsphytochemicalsRubiaceaesecondary metabolism

Identifiers

PMID36684722
PMCPMC9852862
OpenAlexW4313649656

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.