Evidence map›Paper›PMID 36684590›Full record

ArticleFrontiers in cardiovascular medicine2022

CMR detects decreased myocardial deformation in asymptomatic patients at risk for heart failure.

Djawid Hashemi, Patrick Doeblin, Moritz Blum, Karl Jakob Weiss, Matthias Schneider, Grigorios Korosoglou, Rebecca Elisabeth Beyer, Burkert Pieske, Frank Edelmann, Sebastian Kelle

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Design and rationale of the WE-CARE-HF-CMR trial: Cardiorenal care on wheels for asymptomatic heart failure patients (NCT07185100).Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. CMR-based cardiac phenotyping in different forms of heart failure.The international journal of cardiovascular imaging · 2024
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Djawid HashemiDepartment of Internal Medicine and Cardiology, Charité - Universitätsmedizin Berlin, Charité Campus Virchow Clinic, Berlin, Germany.
Patrick DoeblinDepartment of Internal Medicine and Cardiology, German Heart Institute Berlin (DHZB), Berlin, Germany.
Moritz BlumBrookdale Department of Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Karl Jakob WeissDepartment of Internal Medicine and Cardiology, German Heart Institute Berlin (DHZB), Berlin, Germany.
Matthias SchneiderDepartment of Internal Medicine and Cardiology, Charité - Universitätsmedizin Berlin, Charité Campus Virchow Clinic, Berlin, Germany.
Grigorios KorosoglouDepartment of Cardiology, Vascular Medicine and Pneumology, Gesundheitszentrum Rhein-Neckar Hospital Weinheim, Weinheim, Germany.
Rebecca Elisabeth BeyerDepartment of Internal Medicine and Cardiology, Charité - Universitätsmedizin Berlin, Charité Campus Virchow Clinic, Berlin, Germany.
Burkert PieskeDepartment of Internal Medicine and Cardiology, Charité - Universitätsmedizin Berlin, Charité Campus Virchow Clinic, Berlin, Germany.
Frank EdelmannDepartment of Internal Medicine and Cardiology, Charité - Universitätsmedizin Berlin, Charité Campus Virchow Clinic, Berlin, Germany.
Sebastian KelleDepartment of Internal Medicine and Cardiology, Charité - Universitätsmedizin Berlin, Charité Campus Virchow Clinic, Berlin, Germany.
Charité - Universitätsmedizin Berlin · DEGerman Centre for Cardiovascular Research · DEBerlin Heart (Germany) · DEH.W. & J. Hector Stiftung · DEIcahn School of Medicine at Mount Sinai · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: The main management strategy of heart failure with preserved ejection fraction (HFpEF) is prevention since HFpEF is associated with many cardiovascular (CV) risk factors, especially since HFpEF is linked to a high risk for both mortality and recurrent heart failure (HF) hospitalizations. Therefore, there is a need for new tools to identify patients with a high risk profile early. Regional strain assessment by CMR seems to be superior in describing deformation impairment in HF. The MyoHealth score is a promising tool to identify cardiac changes early. Methods and results: Heart failure patients irrespective of LVEF and asymptomatic controls were recruited, and CMR based measures were obtained. For this analysis the asymptomatic control group ( Conclusion: In summary, we show for the first time that asymptomatic subjects with increased CV risk present with HFpEF like impaired myocardial deformation at rest, while they show results like controls under HG stress. The potential of preventive treatment in this group of patients merits further investigation in future. Clinical trial registration: [https://drks.de/search/de/trial/DRKS00015615], identifier [DRKS00015615].

Indexed as

asymptomaticcardiovascular magnetic resonance imaginghandgrip exerciseheart failuremyocardial deformationriskstrain

Identifiers

PMID36684590
PMCPMC9849678
OpenAlexW4313568953

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.