Evidence map›Paper›PMID 36684569›Full record

ArticleFrontiers in cardiovascular medicine2022

Trends in outcomes of women with myocardial infarction undergoing primary angioplasty-Analysis of randomized trials.

Zuzana Motovska, Ota Hlinomaz, Michael Aschermann, Jiri Jarkovsky, Michael Želízko, Petr Kala, Ladislav Groch, Michal Svoboda, Milan Hromadka, Petr Widimsky

Abstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zuzana MotovskaCardiocentre, Third Faculty of Medicine, Charles University and University Hospital Kralovske Vinohrady, Prague, Czechia.
Ota HlinomazDepartment of Cardioangiology, International Clinical Research Center, St. Anne's University Hospital Brno, Brno, Czechia.
Michael AschermannDepartment of Cardiovascular Medicine, First Faculty of Medicine, Charles University, General University Hospital, Prague, Czechia.
Jiri JarkovskyInstitute of Biostatistics and Analyses Ltd., Faculty of Medicine, Masaryk University, Brno, Czechia.
Michael ŽelízkoDepartment of Cardiology, Institute of Clinical and Experimental Medicine, Prague, Czechia.
Petr KalaDepartment of Internal and Cardiology, Faculty of Medicine, Masaryk University and University Hospital Brno-Bohunice, Brno, Czechia.
Ladislav GrochDepartment of Cardioangiology, International Clinical Research Center, St. Anne's University Hospital Brno, Brno, Czechia.
Michal SvobodaDepartment of Cardiology, Institute of Clinical and Experimental Medicine, Prague, Czechia.
Milan HromadkaDepartment of Cardiology, Charles University, University Hospital in Pilsen, Pilsen, Czechia.
Petr WidimskyCardiocentre, Third Faculty of Medicine, Charles University and University Hospital Kralovske Vinohrady, Prague, Czechia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Sex- and gender-associated differences determine the disease response to treatment. Aim: The study aimed to explore the hypothesis that progress in the management of STE-myocardial infarction (STEMI) overcomes the worse outcome in women. Methods and results: We performed an analysis of three randomized trials enrolling patients treated with primary PCI more than 10 years apart. PRAGUE-1,-2 validated the preference of transport for primary PCI over on-site fibrinolysis. PRAGUE-18 enrollment was ongoing at the time of the functional network of 24/7PCI centers, and the intervention was supported by intensive antiplatelets. The proportion of patients with an initial Killip ≥ 3 was substantially higher in the more recent study (0.6 vs. 6.7%, Conclusion: The prognosis of women with MI treated with primary PCI improved substantially with 24/7 regional availability of mechanical reperfusion, performance-enhancing technical progress, and intensive adjuvant antithrombotic therapy. A major modifiable hindrance to achieving this benefit in a broad population of women is the timely diagnosis by health professional services.

Indexed as

mortalitymyocardial infarctionoutcomeprimary PCItherapy managementtrendswomen

Identifiers

PMID36684569
PMCPMC9845716

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.