Evidence map›Paper›PMID 36684508›Full record

ArticleFrontiers in tropical diseases2023

Application of loop mediated isothermal amplification (LAMP) assays for the detection of

Glory Ngongeh Amambo, Ngong Innocentia, Raphael Awah Abong, Fanny Fri Fombad, Abdel Jelil Njouendou, Franck Nietcho, Relindis Ekanya, Chi Anizette Kien, Rene Ebai, Benjamin Lenz and 12 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in tropical diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Pathogens (Basel, Switzerland) · 2024
    Article
  7. Article
  8. Article
  9. Molecular surveillance detects high prevalence of the neglected parasitemedRxiv : the preprint server for health sciences · 2023
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 5 institutions in 5 countries.

Glory Ngongeh AmamboParasites and Vector Research Unit (PAVRU), Department of Microbiology and Parasitology, University of Buea, Buea, Cameroon.
Ngong InnocentiaParasites and Vector Research Unit (PAVRU), Department of Microbiology and Parasitology, University of Buea, Buea, Cameroon.
Raphael Awah AbongParasites and Vector Research Unit (PAVRU), Department of Microbiology and Parasitology, University of Buea, Buea, Cameroon.
Fanny Fri FombadParasites and Vector Research Unit (PAVRU), Department of Microbiology and Parasitology, University of Buea, Buea, Cameroon.
Abdel Jelil NjouendouParasites and Vector Research Unit (PAVRU), Department of Microbiology and Parasitology, University of Buea, Buea, Cameroon.
Franck NietchoParasites and Vector Research Unit (PAVRU), Department of Microbiology and Parasitology, University of Buea, Buea, Cameroon.
Relindis EkanyaParasites and Vector Research Unit (PAVRU), Department of Microbiology and Parasitology, University of Buea, Buea, Cameroon.
Chi Anizette KienParasites and Vector Research Unit (PAVRU), Department of Microbiology and Parasitology, University of Buea, Buea, Cameroon.
Rene EbaiParasites and Vector Research Unit (PAVRU), Department of Microbiology and Parasitology, University of Buea, Buea, Cameroon.
Benjamin LenzInstitute of Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Bonn, Germany.
Manuel RitterInstitute of Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Bonn, Germany.
Mathias Eyong EsumParasites and Vector Research Unit (PAVRU), Department of Microbiology and Parasitology, University of Buea, Buea, Cameroon.
Kebede DeribeGlobal Health and Infection Department, Brighton and Sussex Medical School, Brighton, United Kingdom.
Jerome Fru ChoParasites and Vector Research Unit (PAVRU), Department of Microbiology and Parasitology, University of Buea, Buea, Cameroon.
Amuam Andrew BengParasites and Vector Research Unit (PAVRU), Department of Microbiology and Parasitology, University of Buea, Buea, Cameroon.
Peter Ivo EnyongParasites and Vector Research Unit (PAVRU), Department of Microbiology and Parasitology, University of Buea, Buea, Cameroon.
Zhiru LiNew England Biolabs, Ipswich, MA, United States.
Marc P HübnerInstitute of Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Bonn, Germany.
Kenneth PfarrInstitute of Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Bonn, Germany.
Achim HoeraufInstitute of Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Bonn, Germany.
Clotilde CarlowNew England Biolabs, Ipswich, MA, United States.
Samuel WanjiParasites and Vector Research Unit (PAVRU), Department of Microbiology and Parasitology, University of Buea, Buea, Cameroon.
University of Buea · CMUniversity Hospital Bonn · DENew England Biolabs (United States) · USBrighton and Sussex Medical School · GBGerman Center for Infection Research · DE

Funding

Wellcome Trust 201900Wellcome Trust 201900/Z/16/Z
6 · The paper itself

Abstract

Conventional diagnosis of filarial infections is based on morphological identification of microfilariae using light microscopy and requires considerable expertise, is time-consuming, and can be subjective. Loop-mediated isothermal amplification (LAMP) has advantages over microscopy or PCR because of its operational simplicity, rapidity and versatility of readout options. LAMP assays represent a major step forward in improved filarial diagnostic tools suitable for low resource settings and field applicability. The study goal was to retrospectively evaluate the performance and suitability of the O-150, RF4, and Mp419 LAMP assays for diagnosing

Indexed as

diagnostic testLAMP (loop mediated isothermal amplification)Loa loaMansonella perstansOnchocerca volvulus

Identifiers

PMID36684508
PMCPMC7614089
OpenAlexW4314434846

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.