ArticleKidney cancer journal : official journal of the Kidney Cancer Association2022
SETD2 regulates the methylation of translation elongation factor eEF1A1 in clear cell renal cell carcinoma.
Article in Kidney cancer journal : official journal of the Kidney Cancer Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The trial behind it
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Who cites it
5 citing papers in PubMed, 7 citations in OpenAlex.
- Translational control of Toxoplasma gondii differentiation.Bioscience reports · 2026Review
- METTL10 attenuates adriamycin-induced podocyte injury by targeting cell dedifferentiation.Scientific reports · 2025Article
- KDM5D histone demethylase mediates p38α inactivation via its enzymatic activity to inhibit cancer progression.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Histone methyltransferase SETD2: An epigenetic driver in clear cell renal cell carcinoma.Frontiers in oncology · 2023Review
- The histone methyltransferase SETD2 negatively regulates cell size.Journal of cell science · 2022Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundSET domain-containing protein 2 (
objectiveInitially, we sought to explore SETD2-dependent changes in lysine methylation of proteins in proximal renal tubule cells. Subsequently, we focused on changes in lysine methylation of the translation elongation factor eEF1A1.
methodsTo accomplish these objectives, we initially performed a systems-wide analysis of protein lysine-methylation and expression in wild type (WT) and
resultsWe observed decreased lysine methylation of the translation elongation factor eEF1A1.
conclusionOverall, these data suggest that
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Identifiers
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Registered trials
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