Evidence map›Paper›PMID 36684479›Full record

ArticleBMJ neurology open2023

Door-in-door-out times for patients with large vessel occlusion ischaemic stroke being transferred for endovascular thrombectomy: a Victorian state-wide study.

Joseph Zhi Wen Wong, Helen M Dewey, Bruce C V Campbell, Peter J Mitchell, Mark Parsons, Thanh Phan, Ronil V Chandra, Henry Ma, Alexandra Warwick, Mark Brooks and 12 more

Abstract read
In one paragraph

Article in BMJ neurology open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Joseph Zhi Wen WongDepartment of Neurosciences, Eastern Health, Box Hill, Victoria, Australia.ORCID 0000-0003-0734-8328
Helen M DeweyDepartment of Neurosciences, Eastern Health, Box Hill, Victoria, Australia.ORCID 0000-0001-9484-2070
Bruce C V CampbellDepartments of Medicine and Neurology, Melbourne Brain Centre at The Royal Melbourne Hospital, Parkville, Victoria, Australia.
Peter J MitchellDepartment of Radiology, The Royal Melbourne Hospital, Parkville, Victoria, Australia.
Mark ParsonsDepartments of Medicine and Neurology, Melbourne Brain Centre at The Royal Melbourne Hospital, Parkville, Victoria, Australia.
Thanh PhanDepartment of Neurology, Monash Health, Clayton, Victoria, Australia.
Ronil V ChandraSchool of Clinical Sciences at Monash Health, Department of Medicine, Monash University, Clayton, Victoria, Australia.
Henry MaDepartment of Neurology, Monash Health, Clayton, Victoria, Australia.
Alexandra WarwickDepartment of Neurology, Austin Health, Heidelberg, Victoria, Australia.
Mark BrooksDepartment of Radiology, Austin Health, Heidelberg, Victoria, Australia.
Vincent ThijsDepartment of Neurology, Austin Health, Heidelberg, Victoria, Australia.
Essie LowDepartments of Medicine and Neurology, Melbourne Brain Centre at The Royal Melbourne Hospital, Parkville, Victoria, Australia.
Tissa WijeratneDepartment of Neurology, Western Health, Footscray, Victoria, Australia.ORCID 0000-0002-1701-7111
Sharon JonesDepartment of Neurology, Barwon Health, Geelong, Victoria, Australia.
Ben ClissoldDepartment of Neurology, Barwon Health, Geelong, Victoria, Australia.ORCID 0000-0002-9747-9817
Mei Yan NgunDepartment of Neurology, Northern Hospital Epping, Epping, Victoria, Australia.
Douglas CromptonDepartment of Neurology, Northern Hospital Epping, Epping, Victoria, Australia.
Rumes Kanna SriamareswaranDepartment of Neurology, Peninsula Health, Frankston, Victoria, Australia.
Jayantha RupasingheDepartment of Neurology, Peninsula Health, Frankston, Victoria, Australia.
Karen SmithCentre for Research and Evaluation, Ambulance Victoria, Doncaster, Victoria, Australia.
Chris BladinVictorian Stroke Telemedicine, The Florey Institute of Neuroscience and Mental Health, Parkville, Victoria, Australia.
Philip M C ChoiDepartment of Neurosciences, Eastern Health, Box Hill, Victoria, Australia.ORCID 0000-0003-0339-3439

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Time to reperfusion is an important predictor of outcome in ischaemic stroke from large vessel occlusion (LVO). For patients requiring endovascular thrombectomy (EVT), the transfer times from peripheral hospitals in metropolitan and regional Victoria, Australia to comprehensive stroke centres (CSCs) have not been studied. Aims: To determine transfer and journey times for patients with LVO stroke being transferred for consideration of EVT. Methods: All patients transferred for consideration of EVT to three Victorian CSCs from January 2017 to December 2018 were included. Travel times were obtained from records matched to Ambulance Victoria and the referring centre via Victorian Stroke Telemedicine or hospital medical records. Metrics of interest included door-in-door-out time (DIDO), inbound journey time and outbound journey time. Results: Data for 455 transferred patients were obtained, of which 395 (86.8%) underwent EVT. The median DIDO was 107 min (IQR 84-145) for metropolitan sites and 132 min (IQR 108-167) for regional sites. At metropolitan referring hospitals, faster DIDO was associated with use of the same ambulance crew to transport between hospitals (75 (63-90) vs 124 (99-156) min, p<0.001) and the administration of thrombolysis prior to transfer (101 (79-133) vs 115 (91-155) min, p<0.001). At regional centres, DIDO was consistently longer when patients were transported by air (160 (127-195) vs 116 (100-144) min, p<0.001). The overall door-to-door time by air was shorter than by road for sites located more than 250 km away from the CSC. Conclusion: Transfer times differ significantly for regional and metropolitan patients. A state-wide database to prospectively collect data on all interhospital transfers for EVT would be helpful for future study of optimal transport mode at regional sites and benchmarking of DIDO across the state.

Indexed as

cerebrovascular diseaseinterventionalstroke

Identifiers

PMID36684479
PMCPMC9853123

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.