Evidence map›Paper›PMID 36684433›Full record

ArticleFrontiers in cell and developmental biology2022

Conditioned medium from human cord blood mesenchymal stem cells attenuates age-related immune dysfunctions.

Bo Sun, Xianhui Meng, Yumin Li, Yanlong Li, Rui Liu, Zhongdang Xiao

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cell and developmental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Is Thymic Involution Truly a Deterioration or an Adaptation?Bulletin of mathematical biology · 2026
    Article
  2. Article
  3. A Comprehensive Review of Stem Cell Conditioned Media Role for Anti-Aging on Skin.Stem cells and cloning : advances and applications · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Bo SunState key laboratory of bioelectronics, school of biological science and medical engineering, Southeast University, Nanjing, China.
Xianhui MengState key laboratory of bioelectronics, school of biological science and medical engineering, Southeast University, Nanjing, China.
Yumin LiState key laboratory of bioelectronics, school of biological science and medical engineering, Southeast University, Nanjing, China.
Yanlong LiShandong Electric Power Central Hospital, Jinan, China.
Rui LiuDepartment of Genetic Engineering, College of Natural Science, University of Suwon, Hwaseong-si, South Korea.
Zhongdang XiaoState key laboratory of bioelectronics, school of biological science and medical engineering, Southeast University, Nanjing, China.
State Key Laboratory of Digital Medical EngineeringJinan Central Hospital · CNSoutheast University · CNUniversity of Suwon · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aging is accompanied with progressive deterioration of immune responses and tissue's function. Using 12-month-old mice as model, we showed that conditioned medium of human cord blood mesenchymal stem cells (CBMSC-CM) significantly reduced the population percentage of CD3

Indexed as

anti-agingcord bloodimmune regulationmesenchymal stem cellsoxidative damage

Identifiers

PMID36684433
PMCPMC9846238
OpenAlexW4313482875

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.