ArticleFrontiers in surgery2022
Prediction of osteoporosis from proximal femoral cortical bone thickness and Hounsfield unit value with clinical significance.
Article in Frontiers in surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.
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Who cites it
9 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Opportunistic CT-based osteoporosis screening of the hip: a systematic review of diagnostic accuracy.Archives of orthopaedic and trauma surgery · 2025Pooled it
- Pooled it
- Optimizing plate working length and screw configuration for femoral shaft plate fixation: a finite element analysis under different bone quality scenarios.BMC musculoskeletal disorders · 2026Article
- Improved Osteoporosis Prediction in Breast Cancer Patients Using a Novel Semi-Foundational Model.Journal of imaging informatics in medicine · 2025Article
- Hounsfield unit to serum pentosidine ratio predicts screw loosening after lumbar interbody fusion.BMC musculoskeletal disorders · 2024Article
- Impact of Patient-Specific Hip Joint Geometry on the Morphology of Acetabular Fractures.Journal of clinical medicine · 2024Article
- Article
- Fully Automatic Deep Learning Model for Spine Refracture in Patients with OVCF: A Multi-Center Study.Orthopaedic surgery · 2024Article
- Predictive Value of Dual-Energy CT-Derived Metrics for the Use of Bone Substitutes in Distal Radius Fracture Surgery.Diagnostics (Basel, Switzerland) · 2024Article
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9 authors.
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Abstract
Background: Utilizing dual-energy x-ray absorptiometry (DXA) to assess bone mineral density (BMD) was not routine in many clinical scenarios, leading to missed diagnoses of osteoporosis. The objective of this study is to obtain effective parameters from hip computer tomography (CT) to screen patients with osteoporosis and predict their clinical outcomes. Methods: A total of 375 patients with hip CT scans for intertrochanteric fracture were included. Among them, 56 patients possessed the data of both hip CT scans and DXA and were settled as a training group. The cortical bone thickness (CTh) and Hounsfield unit (HU) values were abstracted from 31 regions of interest (ROIs) of the proximal femur. In the training group, the correlations between these parameters and BMD were investigated, and their diagnostic efficiency of osteoporosis was assessed. Finally, 375 patients were divided into osteoporotic and nonosteoporotic groups based on the optimal cut-off values, and the clinical difference between subgroups was evaluated. Results: The CTh value of ROI 21 and the HU value of ROI 14 were moderately correlated with the hip BMD [ Conclusion: The CTh and HU values of specific cortex sites in the proximal femur were positively correlated with BMD of DXA at the hip. Thresholds for osteoporosis based on CTh and HU values could be utilized to screen osteoporosis and predict clinical outcomes.
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