Evidence map›Paper›PMID 36684072›Full record

ArticleBioengineering & translational medicine2023

Bio-functional hydrogel with antibacterial and anti-inflammatory dual properties to combat with burn wound infection.

Yahui Xiong, Yingbin Xu, Fei Zhou, Yanke Hu, Jingling Zhao, Zhonghua Liu, Qiyi Zhai, Shaohai Qi, Zhaoqiang Zhang, Lei Chen

Abstract read
In one paragraph

Article in Bioengineering & translational medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

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  11. Effect of collagen hydrogel containingIranian journal of microbiology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yahui XiongDepartment of Burns, Laboratory of General Surgery The First Affiliated Hospital, SunYat-Sen University Guangzhou China.
Yingbin XuDepartment of Burns, Laboratory of General Surgery The First Affiliated Hospital, SunYat-Sen University Guangzhou China.
Fei ZhouDepartment of Burns, Laboratory of General Surgery The First Affiliated Hospital, SunYat-Sen University Guangzhou China.
Yanke HuDepartment of Burns, Laboratory of General Surgery The First Affiliated Hospital, SunYat-Sen University Guangzhou China.
Jingling ZhaoDepartment of Burns, Laboratory of General Surgery The First Affiliated Hospital, SunYat-Sen University Guangzhou China.
Zhonghua LiuSouth China Agricultural University Guangzhou China.
Qiyi ZhaiZhuJiang Hospital Southern Medical University Guangzhou China.
Shaohai QiDepartment of Burns, Laboratory of General Surgery The First Affiliated Hospital, SunYat-Sen University Guangzhou China.
Zhaoqiang ZhangDepartment of Oral and Maxillofacial Surgery Stomatological Hospital, Southern Medical University Guangzhou China.ORCID https://orcid.org/0000-0002-9183-7273
Lei ChenDepartment of Burns, Laboratory of General Surgery The First Affiliated Hospital, SunYat-Sen University Guangzhou China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Burn infection delays wound healing and increases the burn patient mortality. Consequently, a new dressing with antibacterial and anti-inflammatory dual properties is urgently required for wound healing. In this study, we propose a combination of methacrylate gelatin (GelMA) hydrogel system with silver nanoparticles embed in γ-cyclodextrin metal-organic frameworks (Ag@MOF) and hyaluronic acid-epigallocatechin gallate (HA-E) for the burn wound infection treatment. Ag@MOF is used as an antibacterial agent and epigallocatechin gallate (EGCG) has exhibited biological properties of anti-inflammation and antibacterial. The GelMA/HA-E/Ag@MOF hydrogel enjoys suitable physical properties and sustained release of Ag

Indexed as

Ag‐metal–organic frameworkburn wound infectionepigallocatechin gallatemacrophage polarizationmethacrylate gelatin

Identifiers

PMID36684072
PMCPMC9842067

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.