Evidence map›Paper›PMID 36684013›Full record

ArticleFrontiers in psychiatry2022

Psychiatric traits and intracerebral hemorrhage: A Mendelian randomization study.

Qingduo Wang, Yajie Qi, Yuping Li, Zhengcun Yan, Xiaodong Wang, Qiang Ma, Can Tang, Xiaoguang Liu, Min Wei, Hengzhu Zhang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Schizophrenia and Types of Stroke: A Mendelian Randomization Study.Journal of the American Heart Association · 2024
    Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Qingduo WangDepartment of Neurosurgery, The Yangzhou School of Clinical Medicine of Dalian Medical University, Dalian, China.
Yajie QiDepartment of Neurosurgery, Clinical Medical College, Yangzhou University, Yangzhou, China.
Yuping LiDepartment of Neurosurgery, Clinical Medical College, Yangzhou University, Yangzhou, China.
Zhengcun YanDepartment of Neurosurgery, Clinical Medical College, Yangzhou University, Yangzhou, China.
Xiaodong WangDepartment of Neurosurgery, Clinical Medical College, Yangzhou University, Yangzhou, China.
Qiang MaDepartment of Neurosurgery, Clinical Medical College, Yangzhou University, Yangzhou, China.
Can TangDepartment of Neurosurgery, Clinical Medical College, Yangzhou University, Yangzhou, China.
Xiaoguang LiuDepartment of Neurosurgery, Clinical Medical College, Yangzhou University, Yangzhou, China.
Min WeiDepartment of Neurosurgery, Clinical Medical College, Yangzhou University, Yangzhou, China.
Hengzhu ZhangDepartment of Neurosurgery, Clinical Medical College, Yangzhou University, Yangzhou, China.
Yangzhou University · CNDalian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Psychiatric traits have been associated with intracerebral hemorrhage (ICH) in observational studies, although their causal relationships remain uncertain. We used Mendelian randomization analyses to infer causality between psychiatric traits and ICH. Methods: We collected data from genome-wide association studies of ICH ( Results: Mendelian randomization analyses revealed suggestive positive causality of mood swings on ICH (odds ratio = 1.006, 95% confidence interval = 1.001-1.012, Conclusion: Our study revealed that mood swings are suggestively causal of ICH and increase the risk of ICH. These results suggest the clinical significance of controlling mood swings for ICH prevention.

Indexed as

causalitygenome-wide association studyintracerebral hemorrhageMendelian randomizationpsychiatric traits

Identifiers

PMID36684013
PMCPMC9850495
OpenAlexW4313546794

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.