Evidence map›Paper›PMID 36683847›Full record

ArticleFrontiers in molecular neuroscience2022

Pre-existing

Tamara L Baker, Alessandro D Uboldi, Christopher J Tonkin, David K Wright, Anh Vo, Trevor Wilson, Richelle Mychasiuk, Stuart J McDonald, Bridgette D Semple, Mujun Sun and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Tamara L BakerDepartment of Neuroscience, Central Clinical School, Monash University, Melbourne, VIC, Australia.
Alessandro D UboldiDivision of Infectious Disease and Immune Defense, Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
Christopher J TonkinDivision of Infectious Disease and Immune Defense, Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
David K WrightDepartment of Neuroscience, Central Clinical School, Monash University, Melbourne, VIC, Australia.
Anh VoMonash Health Translation Precinct, Monash University, Melbourne, VIC, Australia.
Trevor WilsonMonash Health Translation Precinct, Monash University, Melbourne, VIC, Australia.
Richelle MychasiukDepartment of Neuroscience, Central Clinical School, Monash University, Melbourne, VIC, Australia.
Stuart J McDonaldDepartment of Neuroscience, Central Clinical School, Monash University, Melbourne, VIC, Australia.
Bridgette D SempleDepartment of Neuroscience, Central Clinical School, Monash University, Melbourne, VIC, Australia.
Mujun SunDepartment of Neuroscience, Central Clinical School, Monash University, Melbourne, VIC, Australia.
Sandy R ShultzDepartment of Neuroscience, Central Clinical School, Monash University, Melbourne, VIC, Australia.
Monash University · AUWalter and Eliza Hall Institute of Medical Research · AUMonash Health · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Post-traumatic epilepsy (PTE) is a debilitating chronic outcome of traumatic brain injury (TBI), and neuroinflammation is implicated in increased seizure susceptibility and epileptogenesis. However, how common clinical factors, such as infection, may modify neuroinflammation and PTE development has been understudied. The neurotropic parasite, Methods: This study aimed to provide insight into this knowledge gap by assessing how a pre-existing Results: Although no synergistic effects were evident between infection and TBI, chronic Discussion: Our data suggests that a pre-existing

Indexed as

epileptogenesisimmune responseneuroinflammationoxidative stresspost-traumatic epilepsy (PTE)

Identifiers

PMID36683847
PMCPMC9849700
OpenAlexW4313569276

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.