Evidence map›Paper›PMID 36683753›Full record

ArticleRegenerative biomaterials2023

Degradation behavior and osseointegration of Mg-Zn-Ca screws in different bone regions of growing sheep: a pilot study.

Romy Marek, Hanna Ćwieka, Nicholas Donohue, Patrick Holweg, Julian Moosmann, Felix Beckmann, Iva Brcic, Uwe Yacine Schwarze, Kamila Iskhakova, Marwa Chaabane and 5 more

Open access · goldAbstract read
In one paragraph

Article in Regenerative biomaterials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Bioactive materials · 2025
    Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Bioactive materials · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 4 countries.

Romy MarekDepartment of Orthopaedics and Traumatology, Medical University of Graz, 8010 Graz, Austria.
Hanna ĆwiekaInstitute of Metallic Biomaterials, Helmholtz-Zentrum Hereon GmbH, 21502 Geesthacht, Germany.
Nicholas DonohueNational Institute for Bioprocessing Research and Training, University College Dublin, Dublin 4, Ireland.
Patrick HolwegDepartment of Orthopaedics and Traumatology, Medical University of Graz, 8010 Graz, Austria.
Julian MoosmannInstitute of Materials Physics, Helmholtz-Zentrum Hereon GmbH, 21502 Geesthacht, Germany.
Felix BeckmannInstitute of Materials Physics, Helmholtz-Zentrum Hereon GmbH, 21502 Geesthacht, Germany.
Iva BrcicD&R Institute of Pathology, Medical University of Graz, 8010 Graz, Austria.
Uwe Yacine SchwarzeDepartment of Orthopaedics and Traumatology, Medical University of Graz, 8010 Graz, Austria.
Kamila IskhakovaInstitute of Metallic Biomaterials, Helmholtz-Zentrum Hereon GmbH, 21502 Geesthacht, Germany.
Marwa ChaabaneSCANCO Medical AG, 8306 Wangen-Brüttisellen, Switzerland.
Sandra SefaInstitute of Metallic Biomaterials, Helmholtz-Zentrum Hereon GmbH, 21502 Geesthacht, Germany.
Berit Zeller-PlumhoffInstitute of Metallic Biomaterials, Helmholtz-Zentrum Hereon GmbH, 21502 Geesthacht, Germany.
Annelie-Martina WeinbergDepartment of Orthopaedics and Traumatology, Medical University of Graz, 8010 Graz, Austria.
Regine Willumeit-RömerInstitute of Metallic Biomaterials, Helmholtz-Zentrum Hereon GmbH, 21502 Geesthacht, Germany.
Nicole Gabriele SommerDepartment of Orthopaedics and Traumatology, Medical University of Graz, 8010 Graz, Austria.ORCID https://orcid.org/0000-0001-6578-0747
Helmholtz-Zentrum Hereon · DEMedical University of Graz · ATScanco Medical (Switzerland) · CHUniversity College Dublin · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Magnesium (Mg)-based implants are highly attractive for the orthopedic field and may replace titanium (Ti) as support for fracture healing. To determine the implant-bone interaction in different bony regions, we implanted Mg-based alloy ZX00 (Mg < 0.5 Zn < 0.5 Ca, in wt%) and Ti-screws into the distal epiphysis and distal metaphysis of sheep tibiae. The implant degradation and osseointegration were assessed

Indexed as

biodegradable implantscomputed tomographyhistologymagnesium-based alloysMg–Zn–Casheep

Identifiers

PMID36683753
PMCPMC9845522
OpenAlexW4306701925

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.