Evidence map›Paper›PMID 36683711›Full record

ReviewWorld journal of gastroenterology2023

Current status and future perspectives of radiomics in hepatocellular carcinoma.

Joao Miranda, Natally Horvat, Gilton Marques Fonseca, Jose de Arimateia Batista Araujo-Filho, Maria Clara Fernandes, Charlotte Charbel, Jayasree Chakraborty, Fabricio Ferreira Coelho, Cesar Higa Nomura, Paulo Herman

Abstract readReview
In one paragraph

Review in World journal of gastroenterology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  12. Hepatocellular Carcinoma: A Comprehensive Review.Diseases (Basel, Switzerland) · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Joao MirandaDepartment of Radiology, University of Sao Paulo, Sao Paulo 05403-010, Brazil.
Natally HorvatDepartment of Radiology, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, United States.
Gilton Marques FonsecaDepartment of Gastroenterology, University of Sao Paulo, Sao Paulo 05403-000, Brazil.
Jose de Arimateia Batista Araujo-FilhoDepartment of Radiology, Hospital Sirio-Libanes, Sao Paulo 01308-050, Brazil.
Maria Clara FernandesDepartment of Radiology, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, United States.
Charlotte CharbelDepartment of Radiology, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, United States.
Jayasree ChakrabortyDepartment of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, United States.
Fabricio Ferreira CoelhoDepartment of Gastroenterology, University of Sao Paulo, Sao Paulo 05403-000, Brazil.
Cesar Higa NomuraDepartment of Radiology, University of Sao Paulo, Sao Paulo 05403-000, Brazil.
Paulo HermanDepartment of Gastroenterology, University of Sao Paulo, Sao Paulo 05403-000, Brazil. pherman@uol.com.br.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Given the frequent co-existence of an aggressive tumor and underlying chronic liver disease, the management of hepatocellular carcinoma (HCC) patients requires experienced multidisciplinary team discussion. Moreover, imaging plays a key role in the diagnosis, staging, restaging, and surveillance of HCC. Currently, imaging assessment of HCC entails the assessment of qualitative characteristics which are prone to inter-reader variability. Radiomics is an emerging field that extracts high-dimensional mineable quantitative features that cannot be assessed visually with the naked eye from medical imaging. The main potential applications of radiomic models in HCC are to predict histology, response to treatment, genetic signature, recurrence, and survival. Despite the encouraging results to date, there are challenges and limitations that need to be overcome before radiomics implementation in clinical practice. The purpose of this article is to review the main concepts and challenges pertaining to radiomics, and to review recent studies and potential applications of radiomics in HCC.

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsDiagnostic ImagingHumansRetrospective StudiesHepatocellular carcinomaRadiologyRadiomicsTexture analysis

Identifiers

PMID36683711
PMCPMC9850949

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.