Evidence map›Paper›PMID 36683596›Full record

ReviewInternational journal of nanomedicine2023

The Dual Effect of 3D-Printed Biological Scaffolds Composed of Diverse Biomaterials in the Treatment of Bone Tumors.

Yihang Ma, Boyin Zhang, Huifeng Sun, Dandan Liu, Yuhang Zhu, Qingsan Zhu, Xiangji Liu

Open access · goldAbstract readReview
In one paragraph

Review in International journal of nanomedicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Dynamic Hydrogels in Breast Tumor Models.Gels (Basel, Switzerland) · 2025
    Review
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yihang Ma *Department of Spine Surgery, China-Japan Union Hospital of Jilin University, Changchun, People's Republic of China.ORCID 0000-0002-1123-844X
Boyin Zhang *Department of Spine Surgery, China-Japan Union Hospital of Jilin University, Changchun, People's Republic of China.
Huifeng SunDepartment of Respiratory Medicine, No.964 Hospital of People's Liberation Army, Changchun, People's Republic of China.
Dandan LiuDepartment of Spine Surgery, China-Japan Union Hospital of Jilin University, Changchun, People's Republic of China.
Yuhang ZhuDepartment of Spine Surgery, China-Japan Union Hospital of Jilin University, Changchun, People's Republic of China.
Qingsan ZhuDepartment of Spine Surgery, China-Japan Union Hospital of Jilin University, Changchun, People's Republic of China.
Xiangji LiuDepartment of Spine Surgery, The Second Hospital of Dalian Medical University, Dalian, People's Republic of China.ORCID 0000-0003-2020-5196
Union Hospital · CNDalian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone tumors, including primary bone tumors, invasive bone tumors, metastatic bone tumors, and others, are one of the most clinical difficulties in orthopedics. Once these tumors have grown and developed in the bone system, they will interact with osteocytes and other environmental cells in the bone system's microenvironment, leading to the eventual damage of the bone's physical structure. Surgical procedures for bone tumors may result in permanent defects. The dual-efficacy of tissue regeneration and tumor treatment has made biomaterial scaffolds frequently used in treating bone tumors. 3D printing technology, also known as additive manufacturing or rapid printing prototype, is the transformation of 3D computer models into physical models through deposition, curing, and material fusion of successive layers. Adjustable shape, porosity/pore size, and other mechanical properties are an advantage of 3D-printed objects, unlike natural and synthetic material with fixed qualities. Researchers have demonstrated the significant role of diverse 3D-printed biological scaffolds in the treatment for bone tumors and the regeneration of bone tissue, and that they enhanced various performance of the products. Based on the characteristics of bone tumors, this review synthesized the findings of current researchers on the application of various 3D-printed biological scaffolds including bioceramic scaffold, metal alloy scaffold and nano-scaffold, in bone tumors and discussed the advantages, disadvantages, and future application prospects of various types of 3D-printed biological scaffolds. Finally, the future development trend of 3D-printed biological scaffolds in bone tumor is summarized, providing a theoretical foundation and a larger outlook for the use of biological scaffolds in the treatment of patients with bone tumors.

Indexed as

Biocompatible MaterialsBone NeoplasmsBone RegenerationHumansPorosityPrinting, Three-DimensionalTissue EngineeringTissue ScaffoldsTumor MicroenvironmentBiocompatible Materials3D-printedbone tumorsnanomaterialsscaffolds

Identifiers

PMID36683596
PMCPMC9851059
OpenAlexW4316171105

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.