Evidence map›Paper›PMID 36683501›Full record

ArticleClinical hemorheology and microcirculation2023

Non-invasive evaluation of vascular architecture of focal liver lesions by micro vascular imaging.

Yi-Jie Qiu, Juan Cheng, Dan Zuo, Qi Zhang, Xiao-Fan Tian, Xiu-Yun Lu, Sheng Chen, Yi Dong, Wen-Ping Wang

RetractedAbstract readRetracted Publication
PubMed Publisher
In one paragraph

Article in Clinical hemorheology and microcirculation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

  • Retraction · 2025-11-23Compromised Peer Review · Concerns/Issues about Referencing/Attributions · Concerns/Issues about Third Party Involvement · Investigation by Journal/Publisher ·
  • Retracted
5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Yi-Jie QiuDepartment of Ultrasound, Zhongshan Hospital, Fudan University, Shanghai, China.
Juan ChengDepartment of Ultrasound, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China.
Dan ZuoDepartment of Ultrasound, Zhongshan Hospital, Fudan University, Shanghai, China.
Qi ZhangDepartment of Ultrasound, Zhongshan Hospital, Fudan University, Shanghai, China.
Xiao-Fan TianDepartment of Ultrasound, Zhongshan Hospital, Fudan University, Shanghai, China.
Xiu-Yun LuDepartment of Ultrasound, Zhongshan Hospital, Fudan University, Shanghai, China.
Sheng ChenDepartment of Ultrasound, Zhongshan Hospital, Fudan University, Shanghai, China.
Yi DongDepartment of Ultrasound, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China.
Wen-Ping WangDepartment of Ultrasound, Zhongshan Hospital, Fudan University, Shanghai, China.
Zhongshan Hospital · CNFudan University · CNXinHua Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the value of vascular architecture detected by micro vascular imaging (MVI) in preoperative diagnosis of focal liver lesions (FLLs).

methodsIn this retrospective study, patients with surgery and histopathologically proved or radiologically confirmed FLLs were included. Vascular architecture of FLLs were acquired by color Doppler flow imaging (CDFI) and MVI on LOGIQ™ E20 ultrasound machine (C1-6 convex array probes). Alder semiquantitative analysis (grade 0-3) and morphologic features of blood vessels (pattern a-f) were used to assess the blood flow within the FLLs. Interobserver agreement for evaluating blood flow of FLLs was analyzed. Using Adler's grading or morphologic patterns as diagnostic criteria for malignant FLLs, the diagnostic efficiency was analyzed and compared.

resultsFrom October 2021 and February 2022, 50 patients diagnosed with 40 malignant FLLs and 10 benign FLLs were finally included. The Kappa value within two observers for evaluating the blood flow of FLLs was 0.78 for MVI and 0.55 for CDFI. According to Alder semiquantitative analysis, more high-level blood flow signals (grade 2-3) were detected by MVI than CDFI (P < 0.05). Based on high-level blood flow signals (grade 2-3) and hypervascular supply patterns (pattern e and f), the diagnostic accuracy for malignant FLLs were 76% and 68% for MVI, 56% and 38% for CDFI, respectively.

conclusionMVI is superior to CDFI in evaluating vascular architecture of FLLs. The high-level flow signals and hypervascular pattern detected by MVI have a useful and complementary value in preoperative non-invasive identification of malignant FLLs.

Indexed as

Liver NeoplasmsDiagnosis, DifferentialHumansLiverMicrovesselsRetrospective StudiesSensitivity and SpecificityUltrasonographyblood flowcolor Doppler flow imaging (CDFI)focal liver lesions (FLLs)Micro vascular imaging (MVI)vascular architectures

Identifiers

PMID36683501
OpenAlexW4317614851

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.