Evidence map›Paper›PMID 36683168›Full record

ArticleInternational journal of geriatric psychiatry2023

Delirium is significantly associated with hospital frailty risk score derived from administrative data.

Zhiying Lim, Natalie Ling, Vanda Wen Teng Ho, Nachammai Vidhya, Matthew Zhixuan Chen, Beatrix Ling Ling Wong, Shu Ee Ng, Diarmuid Murphy, Reshma Aziz Merchant

Open access · hybridAbstract read
In one paragraph

Article in International journal of geriatric psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Observational
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Zhiying LimDivision of Geriatric Medicine, Department of Medicine, National University Hospital, Singapore, Singapore.ORCID 0000-0002-1649-3335
Natalie LingDivision of Geriatric Medicine, Department of Medicine, National University Hospital, Singapore, Singapore.
Vanda Wen Teng HoDivision of Geriatric Medicine, Department of Medicine, National University Hospital, Singapore, Singapore.
Nachammai VidhyaDivision of Geriatric Medicine, Department of Medicine, National University Hospital, Singapore, Singapore.
Matthew Zhixuan ChenDivision of Geriatric Medicine, Department of Medicine, National University Hospital, Singapore, Singapore.
Beatrix Ling Ling WongDivision of Geriatric Medicine, Department of Medicine, National University Hospital, Singapore, Singapore.
Shu Ee NgDivision of Geriatric Medicine, Department of Medicine, National University Hospital, Singapore, Singapore.
Diarmuid MurphyDepartment of Orthopaedic Surgery, National University Hospital, Singapore, Singapore.
Reshma Aziz MerchantDivision of Geriatric Medicine, Department of Medicine, National University Hospital, Singapore, Singapore.ORCID 0000-0002-9032-0184
National University Hospital · SGNational University of Singapore · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesDelirium is highly prevalent in hospitalised older adults, under-diagnosed and associated with poor outcomes. We aim to determine (i) association of frailty measured using Hospital Frailty Risk Score (HFRS) with delirium, (ii) impact of delirium on mortality, 30-days readmission, extended length of stay (eLOS) and cost (eCOST).

methodsRetrospective cohort study was conducted on 902 older adults ≥75 years discharged from an academic tertiary hospital between March and September 2021. Data was obtained from hospital administrative database.

resultsDelirium was prevalent in 39.1%, 58.1% were female with mean age 85.3 ± 6.2 years. Patients with delirium were significantly older, had higher HFRS, pneumonia, urinary tract infection (UTI), E.coli and Klebsiella infection, constipation, dehydration, stroke and intracranial bleed, with comorbidities including dementia, diabetes, hypertension, hyperlipidaemia and chronic kidney disease. In-hospital mortality, 30-days mortality, 30-days readmission, median LOS and cost was significantly higher. Delirium was significantly associated with at least intermediate frailty (OR = 3.52; CI = 2.48-4.98), dementia (OR = 2.39; CI = 1.61-3.54), UTI (OR = 1.95; CI = 1.29-2.95), constipation (OR = 2.49; CI = 1.43-4.33), Klebsiella infection (OR = 3.06; CI = 1.28-7.30), dehydration (OR = 2.01; CI = 1.40 - 2.88), 30-day mortality (OR = 2.52; CI = 1.42-4.47), 30-day readmission (OR = 2.18; CI = 1.36-3.48), eLOS (OR = 1.80; CI = 1.30-2.49) and eCOST (OR = 1.67; CI = 1.20-2.35).

conclusionsDelirium was highly prevalent in older inpatients, and associated with dementia, frailty, increased cost, LOS, 30-day readmissions and mortality. Hospital Frailty Risk Score had robust association with delirium and can be auto-populated from electronic medical records. Prospective studies are needed on multicomponent delirium preventive measures in high-risk groups identified by HFRS in acute care settings.

Indexed as

DeliriumDementiaFrailtyAgedAged, 80 and overDehydrationFemaleHospitalsHumansLength of StayMaleRetrospective StudiesRisk Factorscostdeliriumfrailtyoutcomes

Identifiers

PMID36683168
PMCPMC10107161
OpenAlexW4315651467

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.