Evidence map›Paper›PMID 36683104›Full record

SynthesisSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2023

Physical rehabilitation for the management of cancer-related fatigue during cytotoxic treatment: a systematic review with meta-analysis.

Giana Berleze Penna, Douglas Maquart Otto, Tassiana Costa da Silva, Anderson Sartor Pedroni, Fabricio Edler Macagnan

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Current non-pharmacological practices for cancer-related fatigue in oncology rehabilitation: results of a national provider survey.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Symptom clusters and network analysis of patients with intermediate and advanced liver cancer treated with targeted immunotherapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Giana Berleze PennaGraduate Program in Rehabilitation Sciences, Federal University of Health Sciences of Porto Alegre, Sarmento Leite, 245, Porto Alegre, RS, Brazil. gianapenna@gmail.com.
Douglas Maquart OttoDepartment of Physical Therapy, Federal University of Health Sciences of Porto Alegre, Sarmento Leite, 245, Porto Alegre, RS, Brazil.
Tassiana Costa da SilvaPostgraduate Program in Pneumological Sciences, Federal University of Rio Grande do Sul, Ramiro Barcelos, 2400, Porto Alegre, RS, Brazil.
Anderson Sartor PedroniGraduate Program in Rehabilitation Sciences, Federal University of Health Sciences of Porto Alegre, Sarmento Leite, 245, Porto Alegre, RS, Brazil.
Fabricio Edler MacagnanGraduate Program in Rehabilitation Sciences, Federal University of Health Sciences of Porto Alegre, UFCSPA, Sarmento Leite, 245, Porto Alegre, RS, Brazil.
Universidade Federal de Ciências da Saúde de Porto Alegre · BRUniversidade Federal do Rio Grande do Sul · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the effect of physical therapy on cancer-related fatigue (CRF) during cytotoxic anticancer treatment.

methodsSystematic review with meta-analysis of randomized clinical trials published from 2010 to 2021 (EMBASE, MEDLINE, PEDro; SciELO, and LILACS). Studies assessing the effect of supervised physical therapy (IG) for the management of CRF on adults undergoing anticancer treatment compared with a control group (CG) covering usual care or any uncontrolled practice, such as recommendations about exercise and health education, were included in this review.

resultsA total of 22 studies were included in the SR and 21 in the meta-analysis, resulting in 1.992 individuals (CG = 973 and IG = 1.019). There was a reduction in general fatigue [SMD =  - 0.69; 95%CI (- 1.15, - 0.22) p < 0.01; I

conclusionPhysical rehabilitation with moderate intensity promoted greater relief of general and physical fatigue. Even after controlling for high heterogeneity, the quality of evidence, summarized in GRADE, was considered moderate for general fatigue and low for physical fatigue.

Indexed as

Antineoplastic AgentsNeoplasmsAdultExerciseExercise TherapyFatigueHumansQuality of LifeAntineoplastic AgentsAntineoplastic agentsChronic fatigue syndromesPatient outcome assessmentPhysical and rehabilitation medicinePhysical therapy

Identifiers

PMID36683104
OpenAlexW4317716256

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.